[HTML][HTML] Role of epigenetics in biology and human diseases
A Moosavi, AM Ardekani - Iranian biomedical journal, 2016 - ncbi.nlm.nih.gov
For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …
factors. However, the role of epigenetics in human diseases has been considered from a …
Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …
Epigenetic aging in major depressive disorder
Objective: Major depressive disorder is associated with an increased risk of mortality and
aging-related diseases. The authors examined whether major depression is associated with …
aging-related diseases. The authors examined whether major depression is associated with …
In response to abiotic stress, DNA methylation confers epigenetic changes in plants
Epigenetics involves the heritable changes in patterns of gene expression determined by
developmental and abiotic stresses, ie, drought, cold, salinity, trace metals, and heat. Gene …
developmental and abiotic stresses, ie, drought, cold, salinity, trace metals, and heat. Gene …
Advances in the profiling of DNA modifications: cytosine methylation and beyond
Chemical modifications of DNA have been recognized as key epigenetic mechanisms for
maintenance of the cellular state and memory. Such DNA modifications include canonical 5 …
maintenance of the cellular state and memory. Such DNA modifications include canonical 5 …
Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults
Importance Epigenetic studies present unique opportunities to advance schizophrenia
research because they can potentially account for many of its clinical features and suggest …
research because they can potentially account for many of its clinical features and suggest …
DNA methylation and schizophrenia: current literature and future perspective
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …
identity, and emotions. It has no central pathophysiological mechanism and precise …
A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects
The central importance of epigenetics to the aging process is increasingly being recognized.
Here we perform a methylome-wide association study (MWAS) of aging in whole blood DNA …
Here we perform a methylome-wide association study (MWAS) of aging in whole blood DNA …
High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction
Background Genetic influence on DNA methylation is potentially an important mechanism
affecting individual differences in humans. We use next-generation sequencing to assay …
affecting individual differences in humans. We use next-generation sequencing to assay …
Transcriptional profiling identifies novel regulators of macrophage polarization
KY Gerrick, ER Gerrick, A Gupta, SJ Wheelan… - PloS one, 2018 - journals.plos.org
Macrophages are key inflammatory immune cells that display dynamic phenotypes and
functions in response to their local microenvironment. Major advances have occurred in …
functions in response to their local microenvironment. Major advances have occurred in …