Cortico-striatal-thalamic loop circuits of the salience network: a central pathway in psychiatric disease and treatment

SK Peters, K Dunlop, J Downar - Frontiers in systems neuroscience, 2016 - frontiersin.org
The salience network (SN) plays a central role in cognitive control by integrating sensory
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …

Digital addiction and sleep

B Dresp-Langley, A Hutt - … journal of environmental research and public …, 2022 - mdpi.com
In 2020, the World Health Organization formally recognized addiction to digital technology
(connected devices) as a worldwide problem, where excessive online activity and internet …

Brain lesions disrupting addiction map to a common human brain circuit

J Joutsa, K Moussawi, SH Siddiqi, A Abdolahi… - Nature medicine, 2022 - nature.com
Drug addiction is a public health crisis for which new treatments are urgently needed. In rare
cases, regional brain damage can lead to addiction remission. These cases may be used to …

Psychedelics as medicines: an emerging new paradigm

DE Nichols, MW Johnson… - Clinical Pharmacology & …, 2017 - Wiley Online Library
Scientific interest in serotonergic psychedelics (eg, psilocybin and LSD; 5‐HT2A receptor
agonists) has dramatically increased within the last decade. Clinical studies administering …

Transcranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: a consensus paper on the present state of the science and the road ahead

H Ekhtiari, H Tavakoli, G Addolorato, C Baeken… - Neuroscience & …, 2019 - Elsevier
There is growing interest in non-invasive brain stimulation (NIBS) as a novel treatment
option for substance-use disorders (SUDs). Recent momentum stems from a foundation of …

Brain networks underlying vulnerability and resilience to drug addiction

KD Ersche, C Meng, H Ziauddeen… - Proceedings of the …, 2020 - National Acad Sciences
Regular drug use can lead to addiction, but not everyone who takes drugs makes this
transition. How exactly drugs of abuse interact with individual vulnerability is not fully …

Brain network dysfunctions in addiction: a meta-analysis of resting-state functional connectivity

S Tolomeo, R Yu - Translational psychiatry, 2022 - nature.com
Resting-state functional connectivity (rsFC) provides novel insights into variabilities in neural
networks associated with the use of addictive drugs or with addictive behavioral repertoire …

Connectome-based prediction of cocaine abstinence

SW Yip, D Scheinost, MN Potenza… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: The authors sought to identify a brain-based predictor of cocaine abstinence by
using connectome-based predictive modeling (CPM), a recently developed machine …

Compulsivity in obsessive–compulsive disorder and addictions

M Figee, T Pattij, I Willuhn, J Luigjes… - European …, 2016 - Elsevier
Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder

YD Ding, X Chen, ZB Chen, L Li, XY Li… - Translational …, 2022 - nature.com
The nucleus accumbens (NAc) is considered a hub of reward processing and a growing
body of evidence has suggested its crucial role in the pathophysiology of major depressive …