Technetium (I) carbonyl complexes for nuclear medicine: Coordination-chemical aspect

GV Sidorenko, AE Miroslavov, MY Tyupina - Coordination Chemistry …, 2023 - Elsevier
Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

A review on evaluation of technetium-99m labeled radiopharmaceuticals

MU Akbar, MR Ahmad, A Shaheen… - Journal of Radioanalytical …, 2016 - Springer
In the past few years, substantial progress has been made in technetium chemistry,
including the synthesis of a variety of 99m Tc-radiopharmaceuticals. This synthesis can be …

Enhanced protective activity of nano formulated andrographolide against arsenic induced liver damage

S Das, GK Pradhan, S Das, D Nath, KD Saha - Chemico-Biological …, 2015 - Elsevier
Chronic exposure to arsenic over a period of time induces toxicity, primarily in liver but
gradually in all systems of the body. Andrographolide (AG), a major diterpene lactone of …

Ursolic Acid Loaded PLGA Nanoparticles: in vitro and in vivo Evaluation to Explore Tumor Targeting Ability on B16F10 Melanoma Cell Lines

R Baishya, DK Nayak, D Kumar, S Sinha… - Pharmaceutical …, 2016 - Springer
Purpose Ursolic acid (UA), a pentacyclic triterpenoid extracted from plants, shows promising
inhibitory effect in different tumor bearing cell lines. In the present study we fabricated UA …

99mTc-amitrole as a novel selective imaging probe for solid tumor: in silico and preclinical pharmacological study

BM Essa, TM Sakr, MA Khedr, FA El-Essawy… - European Journal of …, 2015 - Elsevier
Lactoperoxidase (LPO) inhibitors are very selective for solid tumor due to their high binding
affinity to the LPO enzyme. A computational study was used to select top-ranked LPO …

Design of 5-fluorouracil (5-FU) loaded, folate conjugated peptide linked nanoparticles, a potential new drug carrier for selective targeting of tumor cells

J Kazi, R Mukhopadhyay, R Sen, T Jha, S Ganguly… - …, 2019 - pubs.rsc.org
In the present investigation folate peptide (FA-Pep) conjugated 5-fluorouracil (5-FU) loaded
nanoparticles were synthesized and their tumor targeting potentiality was monitored by …

Radioiodinated doxorubicin as a new tumor imaging model: preparation, biological evaluation, docking and molecular dynamics

AB Ibrahim, M Alaraby Salem, TW Fasih… - … of Radioanalytical and …, 2018 - Springer
Non-invasive molecular imaging techniques are accruing more interest in the last decades.
Several radiolabelling elements have been FDA-approved and are currently used to …

Formulation and preclinical evaluation of 99mTc–gemcitabine as a novel radiopharmaceutical for solid tumor imaging

AB Ibrahim, TM Sakr, OMA Khoweysa… - … of Radioanalytical and …, 2014 - Springer
The aim of this study is the formulation of a new radiopharmaceutical for imaging solid tumor
bearing. Gemcitabine is a nucleoside analogue used as chemotherapeutic agent …

[HTML][HTML] EGFR- and Integrin αVβ3-Targeting Peptides as Potential Radiometal-Labeled Radiopharmaceuticals for Cancer Theranostics

C Rodrigues Toledo, AA Tantawy… - International Journal of …, 2024 - mdpi.com
The burgeoning field of cancer theranostics has witnessed advancements through the
development of targeted molecular agents, particularly peptides. These agents exploit the …

The past, current studies and future of organometallic 99mTc (CO) 3 labeled peptides and proteins

M Piramoon… - Current Pharmaceutical …, 2016 - ingentaconnect.com
The labeling of biomolecule using 99mTc-tricarbonyl is an interesting tool for the diagnosis
of diseases. This labeling startegy has several advantages as compared to other common …