Prolactin is a protein hormone of the anterior pituitary gland that was originally named for its
ability to promote lactation in response to the suckling stimulus of hungry young mammals …

Prolactin is pleotropic in nature affecting multiple tissues throughout the body. As a
consequence of the broad range of functions, regulation of anterior pituitary prolactin …

The growth regulatory effects of PRL on the human breast are mediated by its receptor
(PRLr), a member of the cytokine receptor family. Recent reverse transcriptase-PCR studies …

Normal development and differentiation of the mammary gland are profoundly influenced by
prolactin (PRL). In rodent mammary cancer PRL plays a well defined role, but its role, in …

Knockout (KO) mice have been created that carry null mutations of genes encoding
molecules essential for prolactin (PRL) release, PRL, the receptor for prolactin (PRLR), and …

Zinc (Zn) is required for numerous metabolic processes serving both a structural and
catalytic role. The mammary gland has a unique Zn requirement resulting from the need to …

Prolactin (PRL) is essential for a number of developmental events in the mammary gland.
Work with PRL and PRL receptor knockout mice has shown that PRL indirectly regulates …

The 16 kDa prolactin fragment arises from partial proteolysis of the native 23 kDa prolactin
pituitary hormone. The mammary gland has been involved in this processing, although it has …

The regulation of milk trace mineral homeostasis requires the temporal integration of three
main processes,(A) mineral uptake into the secretory mammary epithelial cell (MEC); …

Pigeon 'milk'and mammalian milk have functional similarities in terms of nutritional benefit
and delivery of immunoglobulins to the young. Mammalian milk has been clearly shown to …