The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Chromogranin A (CHGA), a member of the granin family of proteins, has been an attractive
therapeutic target and candidate biomarker for several cardiovascular, neurological, and …

Hypertension is a common hereditary syndrome with unclear pathogenesis. Chromogranin
A (Chga), which catalyzes formation and cargo storage of regulated secretory granules in …

Background—Oxidative stress, an excessive production of reactive oxygen species (ROS)
outstripping antioxidant defense mechanisms, occurs in cardiovascular pathologies …

After the recent description of the human genome by the ENCODE and the FANTOM
consortia, major attention has been addressed to the so-called “genomic noise”, which …

Chromogranin A (CHGA) is ubiquitously expressed in secretory cells of the endocrine,
neuroendocrine, and neuronal tissues. Although this protein has long been known as a …

Chromogranin A (CHGA/Chga) has been implicated in the genesis of systemic hypertension
and consequent cardiac abnormalities. Catestatin (CST)(human CHGA352-372) …

Recent advances in genome technology have enabled genome-wide searching for disease
predisposition loci, using dense SNP and haplotype maps. Over the past year, such …

Hypertension is a complex trait with deranged autonomic control of the circulation. The
sympathoadrenal system exerts minute-to-minute control over cardiac output and vascular …

Chromogranin A (CHGA), a protein released from secretory granules of chromaffin cells and
sympathetic nerves, triggers endothelin-1 release from endothelial cells. CHGA …