Macrophage receptors and immune recognition

PR Taylor, L Martinez-Pomares, M Stacey… - Annu. Rev …, 2005 - annualreviews.org
▪ Abstract Macrophages express a broad range of plasma membrane receptors that mediate
their interactions with natural and altered-self components of the host as well as a range of …

Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin.

RJ Ulevitch, PS Tobias - Annual review of immunology, 1995 - europepmc.org
In humans and experimental animals the presence of bacterial lipopolysaccharide
(endotoxin, LPS) signals the presence of gram-negative bacteria. Recognition of LPS …

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

ES Van Amersfoort, TJC Van Berkel… - Clinical microbiology …, 2003 - Am Soc Microbiol
Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

RB Yang, MR Mark, A Gray, A Huang, MH Xie… - Nature, 1998 - nature.com
Vertebrates and invertebrates initiate a series of defence mechanisms following infection by
Gram-negative bacteria by sensing the presence of lipopolysaccharide (LPS), a major …

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

E Hailman, HS Lichenstein, MM Wurfel… - The Journal of …, 1994 - rupress.org
CD14 is a 55-kD protein found as a glycosylphosphatidylinositol (GPI)-anchored protein on
the surface of monocytes, macrophages, and polymorphonuclear leukocytes, and as a …

Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

J Pugin, CC Schürer-Maly, D Leturcq… - Proceedings of the …, 1993 - National Acad Sciences
Myeloid cell activation by lipopolysaccharides (LPS) involves two proteins, plasma LPS-
binding protein (LBP) and cell-membrane CD14. Cell membrane CD14, anchored by a …

CD14: cell surface receptor and differentiation marker

HWL Ziegler-Heitbrock, RJ Ulevitch - Immunology today, 1993 - Elsevier
In the past, CD14 has been viewed simply as a useful marker molecule for monocytes and
macrophages. Now, new findings on its role in binding of LPS-LBP complexes and in signal …

An update on the genetics of atopic dermatitis: scratching the surface in 2009

KC Barnes - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
A genetic basis for atopic dermatitis (AD) has long been recognized. Historic documents
allude to family history of disease as a risk factor. Before characterization of the human …

Soluble CD14 participates in the response of cells to lipopolysaccharide.

EA Frey, DS Miller, TG Jahr, A Sundan… - The Journal of …, 1992 - rupress.org
CD14 is a 55-kD protein found both as a glycosylphosphatidyl inositol-linked protein on the
surface of mononuclear phagocytes and as a soluble protein in the blood. CD14 on the cell …

Defense of the bovine mammary gland by polymorphonuclear neutrophil leukocytes

M Paape, J Mehrzad, X Zhao, J Detilleux… - Journal of mammary …, 2002 - Springer
The primary phagocytic cells of the bovine mammary gland, polymorphonuclear neutrophil
leukocytes (PMN), and macrophages, comprise the first line of defense against invading …