The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Congenital stationary night blindness (CSNB) refers to a group of genetically and clinically
heterogeneous retinal disorders. Seventeen different genes with more than 360 different …

Paraneoplastic syndromes involving the visual system are a heterogeneous group of
disorders occurring in the setting of systemic malignancy. Timely recognition of one of these …

It is now well established that antibodies have numerous potential benefits when developed
as therapeutics. Here, we evaluate the technical challenges of raising antibodies to …

Purpose: To review the current state for diagnosis and management of autoimmune
retinopathy. Methods: A review of the literature was performed, encompassing autoimmune …

Autoantibodies (AAbs) against various retinal proteins have been associated with vision loss
in paraneoplastic and non-paraneoplastic autoimmune retinopathies (AR). There are two …

Autoimmune retinopathy (AIR) refers to a group of rare autoimmune retinal degenerative
diseases presumably caused by cross-reactivity of serum autoantibodies against retinal …

The dark-adapted human electroretinogram (ERG) response to a standard bright flash
includes a negative-going a-wave followed by a positive-going b-wave that crosses the …

Appaloosa horses are predisposed to equine recurrent uveitis (ERU), an immune‐mediated
disease characterized by recurring inflammation of the uveal tract in the eye, which is the …

Masquerade syndromes represent a large set of ophthalmological entities that mimic
inflammatory conditions. Any delay in their diagnosis may be correlated with systemic …