Salivarian trypanosomosis: a review of parasites involved, their global distribution and their interaction with the innate and adaptive mammalian host immune system

M Radwanska, N Vereecke, V Deleeuw… - Frontiers in …, 2018 - frontiersin.org
Salivarian trypanosomes are single cell extracellular parasites that cause infections in a
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …

The molecular arms race between African trypanosomes and humans

E Pays, B Vanhollebeke, P Uzureau… - Nature Reviews …, 2014 - nature.com
Humans can survive bloodstream infection by African trypanosomes, owing to the activity of
serum complexes that have efficient trypanosome-killing ability. The two trypanosome …

Development of transgenic fungi that kill human malaria parasites in mosquitoes

W Fang, J Vega-Rodríguez, AK Ghosh… - Science, 2011 - science.org
Metarhizium anisopliae infects mosquitoes through the cuticle and proliferates in the
hemolymph. To allow M. anisopliae to combat malaria in mosquitoes with advanced malaria …

Evolution of the primate trypanolytic factor APOL1

R Thomson, G Genovese, C Canon… - Proceedings of the …, 2014 - National Acad Sciences
ApolipoproteinL1 (APOL1) protects humans and some primates against several African
trypanosomes. APOL1 genetic variants strongly associated with kidney disease in African …

Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis

R Thomson, A Finkelstein - Proceedings of the National …, 2015 - National Acad Sciences
Apolipoprotein L-1 (APOL1), the trypanolytic factor of human serum, can lyse several African
trypanosome species including Trypanosoma brucei brucei, but not the human-infective …

Fast-track solar cells

MD McGehee - Nature, 2013 - nature.com
Fast-track solar cells | Nature Skip to main content Thank you for visiting nature.com. You are
using a browser version with limited support for CSS. To obtain the best experience, we …

Immunobiology of African trypanosomes: need of alternative interventions

TN Baral - BioMed Research International, 2010 - Wiley Online Library
Trypanosomiasis is one of the major parasitic diseases for which control is still far from
reality. The vaccination approaches by using dominant surface proteins have not been …

The trypanolytic factor of human serum: many ways to enter the parasite, a single way to kill

B Vanhollebeke, E Pays - Molecular microbiology, 2010 - Wiley Online Library
Humans have developed a particular innate immunity system against African trypanosomes,
and only two Trypanosoma brucei clones (T. b. gambiense, T. b. rhodesiense) can resist this …

Cation channel conductance and pH gating of the innate immunity factor APOL1 are governed by pore-lining residues within the C-terminal domain

C Schaub, J Verdi, P Lee, N Terra, G Limon… - Journal of Biological …, 2020 - ASBMB
The human innate immunity factor apolipoprotein LI (APOL1) protects against infection by
several protozoan parasites, including Trypanosoma brucei brucei. Endocytosis and …

[HTML][HTML] 25 years of African trypanosome research: From description to molecular dissection and new drug discovery

KR Matthews - Molecular and Biochemical Parasitology, 2015 - Elsevier
Abstract The Molecular Parasitology conference was first held at the Marine Biological
laboratory, Woods Hole, USA 25 years ago. Since that first meeting, the conference has …