A high-stringency blueprint of the human proteome
Abstract The Human Proteome Organization (HUPO) launched the Human Proteome Project
(HPP) in 2010, creating an international framework for global collaboration, data sharing …
(HPP) in 2010, creating an international framework for global collaboration, data sharing …
Evolution and implications of de novo genes in humans
Genes and translated open reading frames (ORFs) that emerged de novo from previously
non-coding sequences provide species with opportunities for adaptation. When aberrantly …
non-coding sequences provide species with opportunities for adaptation. When aberrantly …
UniProt: the universal protein knowledgebase
Nucleic acids research, 2017 - academic.oup.com
The UniProt knowledgebase is a large resource of protein sequences and associated
detailed annotation. The database contains over 60 million sequences, of which over half a …
detailed annotation. The database contains over 60 million sequences, of which over half a …
Accessing NCBI data using the NCBI sequence viewer and genome data viewer (GDV)
SH Rangwala, A Kuznetsov, V Ananiev… - Genome …, 2021 - genome.cshlp.org
The National Center for Biotechnology Information (NCBI) is an archive providing free
access to a wide range and large volume of biological sequence data and literature. Staff …
access to a wide range and large volume of biological sequence data and literature. Staff …
The neXtProt knowledgebase in 2020: data, tools and usability improvements
M Zahn-Zabal, PA Michel, A Gateau… - Nucleic Acids …, 2020 - academic.oup.com
Abstract The neXtProt knowledgebase (https://www. nextprot. org) is an integrative resource
providing both data on human protein and the tools to explore these. In order to provide …
providing both data on human protein and the tools to explore these. In order to provide …
The 2022 report on the human proteome from the HUPO human proteome project
The 2022 Metrics of the Human Proteome from the HUPO Human Proteome Project (HPP)
show that protein expression has now been credibly detected (neXtProt PE1 level) for 18 …
show that protein expression has now been credibly detected (neXtProt PE1 level) for 18 …
Alternative splicing may not be the key to proteome complexity
Alternative splicing is commonly believed to be a major source of cellular protein diversity.
However, although many thousands of alternatively spliced transcripts are routinely detected …
However, although many thousands of alternatively spliced transcripts are routinely detected …
[HTML][HTML] Human SRMAtlas: a resource of targeted assays to quantify the complete human proteome
U Kusebauch, DS Campbell, EW Deutsch, CS Chu… - Cell, 2016 - cell.com
The ability to reliably and reproducibly measure any protein of the human proteome in any
tissue or cell type would be transformative for understanding systems-level properties as …
tissue or cell type would be transformative for understanding systems-level properties as …
The human plasma proteome draft of 2017: building on the human plasma PeptideAtlas from mass spectrometry and complementary assays
Human blood plasma provides a highly accessible window to the proteome of any individual
in health and disease. Since its inception in 2002, the Human Proteome Organization's …
in health and disease. Since its inception in 2002, the Human Proteome Organization's …
Recommendations for the generation, quantification, storage, and handling of peptides used for mass spectrometry–based assays
BACKGROUND For many years, basic and clinical researchers have taken advantage of the
analytical sensitivity and specificity afforded by mass spectrometry in the measurement of …
analytical sensitivity and specificity afforded by mass spectrometry in the measurement of …