[HTML][HTML] The role of N-glycosylation in cancer

Y Lin, DM Lubman - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Despite advances in understanding the development and progression of cancer in recent
years, there remains a lack of comprehensive characterization of the cancer glycoproteome …

An overview of kinin mediated events in cancer progression and therapeutic applications

K Deepak, PK Roy, P Kola, B Mukherjee… - Biochimica et Biophysica …, 2022 - Elsevier
Kinins are bioactive peptides generated in the inflammatory milieu of the tissue
microenvironment, which is involved in cancer progression and inflammatory response …

Sequential precipitation and delipidation enables efficient enrichment of low-molecular weight proteins and peptides from human plasma

N Li, Y Zhou, J Wang, L Niu, Q Zhang… - Journal of proteome …, 2020 - ACS Publications
Low-molecular weight proteins and peptides (LMWPs,< 30 kDa) in human plasma serve as
potential biomarkers or drug targets and are endowed with desirable traits for biological and …

IDH1, a CHOP and C/EBPβ-responsive gene under ER stress, sensitizes human melanoma cells to hypoxia-induced apoptosis

X Yang, T Du, X Wang, Y Zhang, W Hu, X Du, L Miao… - Cancer letters, 2015 - Elsevier
Abstract Isocitrate dehydrogenase1 (IDH1) is of great importance in cell metabolism and
energy conversion. However, alterations in IDH1 in response to stress and excise-regulated …

Circulating proteolytic products of carboxypeptidase N for early detection of breast cancer

Y Li, Y Li, T Chen, AS Kuklina, P Bernard… - Clinical …, 2014 - academic.oup.com
Abstract BACKGROUND: Carboxypeptidase N (CPN) is important in regulating vasoactive
peptide hormones, growth factors, and cytokines by specifically cleaving their C-terminal …

The peptidome comes of age: mass spectrometry-based characterization of the circulating cancer peptidome

DW Greening, EA Kapp, RJ Simpson - The Enzymes, 2017 - Elsevier
Peptides play a seminal role in most physiological processes acting as neurotransmitters,
hormones, antibiotics, and immune regulation. In the context of tumor biology, it is …

Post-genomics nanotechnology is gaining momentum: nanoproteomics and applications in life sciences

FH Kobeissy, B Gulbakan, A Alawieh… - Omics: a journal of …, 2014 - liebertpub.com
The post-genomics era has brought about new Omics biotechnologies, such as proteomics
and metabolomics, as well as their novel applications to personal genomics and the …

Recent developments in proteomic methods and disease biomarkers

N Bergman, J Bergquist - Analyst, 2014 - pubs.rsc.org
Proteomic methodologies for identification and analysis of biomarkers have gained more
attention during recent years and have evolved rapidly. Identification and detection of …

Antibody-Free Detection of Mycobacterium tuberculosis Antigen Using Customized Nanotraps

HJ Wu, Y Li, J Fan, Z Deng, Z Hu, X Liu… - Analytical …, 2014 - ACS Publications
Rapid screening and diagnosis of tuberculosis disease (TB) is still challenging and critically
needed for global TB control efforts. In this study, we present a rapid and streamlined …

Magnetic mesoporous silica incorporated with TiO 2 for selective and rapid capture of peptides

G Cheng, Y Wang, ZG Wang, XJ Sui, JL Zhang, JZ Ni - RSC Advances, 2014 - pubs.rsc.org
Exploration of valuable information from peptide biomarkers in biological fluids for early
diagnosis and elucidation of disease has drawn increasing attention in clinical biomedicine …