Depolymerization of cellulose to glucose requires the synergistic action of three key
cellulases, endoglucanase (EC 3.2. 1.4), exoglucanase (EC 3.2. 1.176)(EC 3.2. 1.91) and β …

Cold-active enzymes constitute an attractive resource for biotechnological applications.
Their high catalytic activity at temperatures below 25° C makes them excellent biocatalysts …

Lignocellulosic biomass is the earth's most abundant renewable feedstock alternative that
comprises of cellulose, hemi-cellulose and lignin. The synergistic action of …

The ability of psychrophiles to survive and proliferate at low temperatures implies that they
have overcome key barriers inherent to permanently cold environments. These challenges …

By far the largest proportion of the Earth's biosphere is comprised of organisms that thrive in
cold environments (psychrophiles). Their ability to proliferate in the cold is predicated on a …

Psychrophiles thriving permanently at near‐zero temperatures synthesize cold‐active
enzymes to sustain their cell cycle. Genome sequences, proteomic, and transcriptomic …

While the crucial role of intrinsically disordered proteins (IDPs) in the cell cycle is now
recognized, deciphering their molecular mode of action at the structural level still remains …

Identifying relationships between function, amino acid sequence, and protein structure
represents a major challenge. In this study, we propose a bioinformatics approach that …

Psychrophilic microorganisms thrive in permanently cold environments, even at subzero
temperatures. To maintain metabolic rates compatible with sustained life, they have …

The challenges associated with the structural characterization of disordered proteins have
resulted in the application of a host of biophysical methods to such systems. NMR …