Dermatophyte resistance to antifungal drugs: mechanisms and prospectus

NM Martinez-Rossi, TA Bitencourt, NTA Peres… - Frontiers in …, 2018 - frontiersin.org
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …

An update on the myriad antifungal resistance mechanisms in dermatophytes and the place of experimental and existential therapeutic agents for Trichophyton …

K Sardana, S Sharath, A Khurana… - Expert Review of Anti …, 2023 - Taylor & Francis
Introduction There is an epidemic emergence of increased resistance in dermatophytes with
to antifungal drugs with ergosterol1 (Erg1) and Erg11 mutations to terbinafine and azoles …

Paracoccidioides Species Complex: Ecology, Phylogeny, Sexual Reproduction, and Virulence

MM Teixeira, RC Theodoro, G Nino-Vega… - PLoS …, 2014 - journals.plos.org
Paracoccidioidomycosis (PCM) is a deep systemic mycosis caused by human fungal
pathogens of the Paracoccidioides genus. The disease is geographically restricted to …

[HTML][HTML] Heat stress-induced reactive oxygen species participate in the regulation of HSP expression, hyphal branching and ganoderic acid biosynthesis in …

R Liu, X Zhang, A Ren, DK Shi, L Shi, J Zhu… - Microbiological …, 2018 - Elsevier
Heat stress (HS) is an important environmental factor that affects the growth and metabolism
of edible fungi, but the molecular mechanism of the heat stress response (HSR) remains …

Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies

E Camacho, GA Niño-Vega - Mediators of inflammation, 2017 - Wiley Online Library
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

Inhibition of heat-shock protein 90 enhances the susceptibility to antifungals and reduces the virulence of Cryptococcus neoformans/Cryptococcus gattii species …

RA Cordeiro, AJJ Evangelista, R Serpa… - …, 2016 - microbiologyresearch.org
Heat-shock proteins (Hsps) are chaperones required for the maintenance of cellular
homeostasis in different fungal pathogens, playing an important role in the infectious …

Identification and Analysis of the Role of Superoxide Dismutases Isoforms in the Pathogenesis of Paracoccidioides spp.

D Tamayo, JF Muñoz, Á Lopez, M Urán… - PLoS Neglected …, 2016 - journals.plos.org
The ability of Paracoccidioides to defend itself against reactive oxygen species (ROS)
produced by host effector cells is a prerequisite to survive. To counteract these radicals …

New insights into a complex fungal pathogen: the case of Paracoccidioides spp.

A Gonzalez, O Hernandez - Yeast, 2016 - Wiley Online Library
Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with
Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several …

A hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp

P Albuquerque, AM Nicola… - PLoS neglected …, 2019 - journals.plos.org
Paracoccidioides spp. are thermodimorphic fungi that cause a neglected tropical disease (
paracoccidioidomycosis) that is endemic to Latin America. These fungi inhabit the soil …

Heat shock proteins in Histoplasma and Paracoccidioides

LG Cleare, D Zamith-Miranda… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Heat shock proteins (Hsps) are highly conserved biomolecules that are constitutively
expressed and generally upregulated in response to various stress conditions (biotic and …