Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …

Preeclampsia is a complex cardiovascular disorder of pregnancy with underlying
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …

Neprilysin (NEP) is an integral membrane-bound metallopeptidase with a wide spectrum of
substrates and physiological functions. It plays an important role in proteolytic processes in …

Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

For fluorogenic probes, Förster resonance energy transfer (FRET) is one of the most widely
used mechanisms to realize the detection of biochemical activities. Dark quenchers relax …

Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …

Exosomes are a subset of extracellular vesicles with an average diameter of~ 100nm.
Exosomes are released by all cells through an endosome-dependent pathway and carry …

The pathogenesis of preeclampsia begins when a fertilized egg infiltrates the decidua,
resulting in implantation failure (eg, due to extravillous trophoblast infiltration disturbance …

The ability of exosomes to transport different molecular cargoes and their ability to influence
various physiological factors is already well known. An exciting area of research explores …

Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …