Inflammasomes are molecular scaffolds that are activated by damage-associated and
pathogen-associated molecular patterns and form a key element of innate immune …

Tumor-associated epilepsy is the most common presenting symptom in patients diagnosed
with diffuse gliomas. Recent evidence illustrates the requirement of synaptic activity to drive …

Neuroinflammation is a critical component in neurodegenerative disorders. The
inflammasome, facilitates the cleavage of caspase-1, leading to the maturation and …

Neuroinflammation represents a dynamic process of defense and protection against the
harmful action of infectious agents or other detrimental stimuli in the central nervous system …

Epilepsy is a severe central nervous system disorder characterized by an imbalance
between neuronal excitation and inhibition, resulting in heightened neuronal excitability …

Epilepsy is one of the most widespread and complex diseases in the central nervous system
(CNS), affecting approximately 65 million people globally, an important factor resulting in …

Epilepsy is one of the most prevalent and serious brain disorders and affects over 70 million
people globally. Antiseizure medications (ASMs) relieve symptoms and prevent the …

Cerebral small vessel disease (CSVD) is a cerebral vascular disease with insidious onset
and poor clinical treatment effect, the disease is related to neuroinflammation. This study …

Abstract Objective The NLRP3 (NOD-like receptor family, pyrin domain containing 3)
inflammasome-driven immune-inflammatory response has been shown to play a critical role …

Febrile infection-related epilepsy syndrome (FIRES) is a rare epilepsy syndrome with
unclear pathogenesis, characterized by fever-induced, super-refractory status epilepticus …