Cytokines: from clinical significance to quantification

C Liu, D Chu, K Kalantar‐Zadeh, J George… - Advanced …, 2021 - Wiley Online Library
Cytokines are critical mediators that oversee and regulate immune and inflammatory
responses via complex networks and serve as biomarkers for many diseases. Quantification …

[HTML][HTML] Oriented immobilization of antibodies onto sensing platforms-A critical review

S Gao, JM Guisán, J Rocha-Martin - Analytica chimica acta, 2022 - Elsevier
The immunosensor has been proven a versatile tool to detect various analytes, such as food
contaminants, pathogenic bacteria, antibiotics and biomarkers related to cancer. To fabricate …

Antifouling strategies in advanced electrochemical sensors and biosensors

PH Lin, BR Li - Analyst, 2020 - pubs.rsc.org
Electrochemical biosensors have been applied in a broad range of clinical applications for
pathogen biomarker detection and medical applications and diagnosis due to the sensitivity …

Point‐of‐care detection of cytokines in cytokine storm management and beyond: Significance and challenges

G Liu, C Jiang, X Lin, Y Yang - View, 2021 - Wiley Online Library
Cytokines are signaling molecules between cells in immune system. Cytokine storm, due to
the sudden acute increase in levels of pro‐inflammatory circulating cytokines, can result in …

CRISPR/Cas12a-powered immunosensor suitable for ultra-sensitive whole Cryptosporidium oocyst detection from water samples using a plate reader

Y Li, F Deng, T Hall, G Vesey, EM Goldys - Water research, 2021 - Elsevier
Waterborne pathogens, such as Cryptosporidium parvum, pose a major threat to public
health globally, and this requires screening of drinking and environmental water for low …

A CRISPR/Cas12a-assisted on-fibre immunosensor for ultrasensitive small protein detection in complex biological samples

F Deng, Y Li, L Qiao, E Goldys - Analytica Chimica Acta, 2022 - Elsevier
Tracking trace amounts of analytes directly from low volumes of complex biological samples
remains an ongoing challenge in precision diagnostics, as the commonly used …

Functionalization of Polydimethylsiloxane with Diazirine-Based Linkers for Covalent Protein Immobilization

J Li, L Bi, SF Musolino, JE Wulff… - ACS Applied Materials & …, 2023 - ACS Publications
Biomolecule attachment to solid supports is critical for biomedical devices, such as
biosensors and implants. Polydimethylsiloxane (PDMS) is commonly used for these …

Luminescent Surface‐Tethered Polymer Brush Materials

J Poisson, ZM Hudson - Chemistry–A European Journal, 2022 - Wiley Online Library
Surface‐tethered polymers are unique molecular architectures that have been recently used
in advanced sensors, electronics and biomedical applications. However, techniques for …

In vivo intrathecal IL-1β quantification in rats: Monitoring the molecular signals of neuropathic pain

A Arman, F Deng, EM Goldys, G Liu… - Brain, Behavior, and …, 2020 - Elsevier
Background Neuropathic pain, or pain after nerve injury, is a disorder with a significant
reliance on the signalling of cytokines such as IL-1β. However, quantifying the cytokine …

[HTML][HTML] Needle-Shaped Biosensors for Precision Diagnoses: From Benchtop Development to In Vitro and In Vivo Applications

R Xue, F Deng, T Guo, A Epps, NH Lovell… - Biosensors, 2024 - mdpi.com
To achieve the accurate recognition of biomarkers or pathological characteristics within
tissues or cells, in situ detection using biosensor technology offers crucial insights into the …