Protein aggregation: from background to inhibition strategies
The aggregation of specific proteins is hypothesized to cause several pathological
conditions, which are collectively known as amyloid disorders. The aggregation of peptides …
conditions, which are collectively known as amyloid disorders. The aggregation of peptides …
Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?
DB Kell, E Pretorius - Biochemical Journal, 2023 - portlandpress.com
It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …
Vitamin k3 inhibits protein aggregation: implication in the treatment of amyloid diseases
Protein misfolding and aggregation have been associated with several human diseases
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …
Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity
Protein aggregation into oligomers and fibrils are associated with many human
pathophysiologies. Compounds that modulate protein aggregation and interact with …
pathophysiologies. Compounds that modulate protein aggregation and interact with …
Vitamin B12 offers neuronal cell protection by inhibiting Aβ-42 amyloid fibrillation
Protein misfolding and aggregation has been implicated as the cause of more than 20
diseases in humans such as Alzheimer's and Parkinson's and systemic amyloidosis …
diseases in humans such as Alzheimer's and Parkinson's and systemic amyloidosis …
Conditions governing food protein amyloid fibril formation—Part I: Egg and cereal proteins
KJA Jansens, MA Lambrecht… - … reviews in food …, 2019 - Wiley Online Library
Conditions including heating mode, time, temperature, pH, moisture and protein
concentration, shear, and the presence of alcohols, chaotropic/reducing agents, enzymes …
concentration, shear, and the presence of alcohols, chaotropic/reducing agents, enzymes …
Lignin nanoparticles are renewable and functional platforms for the concanavalin a oriented immobilization of glucose oxidase–peroxidase in cascade bio-sensing
E Capecchi, D Piccinino, E Tomaino, BM Bizzarri… - RSC …, 2020 - pubs.rsc.org
Lignin nanoparticles (LNPs) acted as a renewable and efficient platform for the
immobilization of horseradish peroxidase (HRP) and glucose oxidase (GOX) by a layer by …
immobilization of horseradish peroxidase (HRP) and glucose oxidase (GOX) by a layer by …
Anti-amyloidogenic behavior and interaction of diallylsulfide with human serum albumin
In this work, binding of garlic component-Diallysulfide (DAS) with major human blood
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …
Tryptophan fluorescence quenching as a binding assay to monitor protein conformation changes in the membrane of intact mitochondria
Intrinsic protein fluorescence is due to aromatic amino acids, mainly tryptophan, which can
be selectively measured by exciting at 295 nm. Changes in emission spectra of tryptophan …
be selectively measured by exciting at 295 nm. Changes in emission spectra of tryptophan …
A review on protein misfolding, aggregation and strategies to prevent related ailments
This review aims to highlight the fundamental mechanism of protein misfolding leading to
protein aggregation and associated diseases. It also aims to anticipate novel therapeutic …
protein aggregation and associated diseases. It also aims to anticipate novel therapeutic …