The successful assembly of large supramolecular structures infers a delicate balance
between reversible noncovalent interactions which are capable of undergoing correction …

The outer membrane protects Gram‐negative bacteria against a harsh environment. At the
same time, the embedded proteins fulfil a number of tasks that are crucial to the bacterial …

An algorithm has been developed which identifies α-helices involved in the interactions of
membrane proteins with lipid bilayers and which distinguishes them from helices in soluble …

Porins form aqueous channels that aid the diffusion of small hydrophilic molecules across
the outer membrane of Gram-negative bacteria. The crystal structures of matrix porin and …

Detergents are indispensable in the isolation of integral membrane proteins from biological
membranes to study their intrinsic structural and functional properties. Solubilization …

The integral membrane protein porin from Rhodobacter capsulatus consists of three tightly
associated 16-stranded β barrels that give rise to three distinct diffusion channels for small …

Integral membrane proteins come in two types, α-helical and β-barrel proteins. In both types,
all hydrogen bonding donors and acceptors of the polypeptide backbone are completely …

The primary reaction of photosynthesis is light-driven charge separation, carried out in
reaction centres, which are complexes of integral membrane proteins and cofactors. The …

The elucidation of the three dimensional structure of biological macromolecules has
provided an important contribution to our current understanding of many basic mechanisms …

Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …