[HTML][HTML] Hereditary hemorrhagic telangiectasia: diagnosis and management from the hematologist's perspective

A Kritharis, H Al-Samkari, DJ Kuter - Haematologica, 2018 - ncbi.nlm.nih.gov
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu
syndrome, is an autosomal dominant disorder that causes abnormal blood vessel formation …

Hereditary haemorrhagic telangiectasia: pathophysiology, diagnosis and treatment

CL Shovlin - Blood reviews, 2010 - Elsevier
Hereditary haemorrhagic telangiectasia, inherited as an autosomal dominant trait, affects
approximately 1 in 5000 people. The abnormal vascular structures in HHT result from …

European reference network for rare vascular diseases (VASCERN) outcome measures for hereditary haemorrhagic telangiectasia (HHT)

CL Shovlin, E Buscarini, AD Kjeldsen, HJ Mager… - Orphanet Journal of …, 2018 - Springer
Hereditary haemorrhagic telangiectasia (HHT) is a multisystemic vascular dysplasia that
leads to nosebleeds, anaemia due to blood loss, and arteriovenous malformations (AVMs) …

Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease)

V Cottin, S Dupuis-Girod, G Lesca, JF Cordier - Respiration, 2007 - karger.com
Hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler-Weber disease is a genetic
disorder with autosomal dominance and variable penetrance, characterized by epistaxis …

Vascular deficiency of Smad4 causes arteriovenous malformations: a mouse model of Hereditary Hemorrhagic Telangiectasia

AM Crist, AR Lee, NR Patel, DE Westhoff… - Angiogenesis, 2018 - Springer
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder
that leads to abnormal connections between arteries and veins termed arteriovenous …

Embolisation for pulmonary arteriovenous malformation

CCT Hsu, GNC Kwan, H Evans‐Barns… - Cochrane Database …, 2018 - cochranelibrary.com
Background Pulmonary arteriovenous malformations are abnormal direct connections
between the pulmonary artery and pulmonary vein which result in a right‐to‐left shunt. They …

Complications and mortality in hereditary hemorrhagic telangiectasia: a population-based study

JW Donaldson, TM McKeever, IP Hall, RB Hubbard… - Neurology, 2015 - AAN Enterprises
Objectives: Studies report that the risks of significant neurologic complications (including
stroke, cerebral abscess, and migraine) and hemorrhagic sequelae are high in patients with …

Gastrointestinal manifestations of hereditary hemorrhagic telangiectasia (HHT): a systematic review of the literature

SB Jackson, NP Villano, JN Benhammou… - Digestive diseases and …, 2017 - Springer
Hereditary hemorrhagic telangiectasia (HHT), also called Osler–Weber–Rendu syndrome, is
an autosomal dominant genetic disease that affects the vasculature of numerous organs …

Endoglin for targeted cancer treatment

LS Rosen, MS Gordon, F Robert, DE Matei - Current oncology reports, 2014 - Springer
Endoglin is a homodimeric cell membrane glycoprotein receptor for transforming growth
factor β and bone morphogenetic proteins. Endoglin is essential for angiogenesis, being …

The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study

JW Donaldson, TM McKeever, IP Hall, RB Hubbard… - Thorax, 2014 - thorax.bmj.com
Background Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant
genetic disorder of aberrant blood vessel development characterised by arteriovenous …