The optical properties of the ocular lens are important to overall vision quality. As a
transparent biological tissue, the lens contributes to the overall and dynamic focussing …

Tropomodulins are a family of four proteins (Tmods 1–4) that cap the pointed ends of actin
filaments in actin cytoskeletal structures in a developmentally regulated and tissue‐specific …

Planar cell rearrangements control epithelial tissue morphogenesis and cellular pattern
formation. They lead to the formation of new junctions whose length and stability determine …

The primary function of the lens resides in its transparency and ability to focus light on the
retina. These require both that the lens cells contain high concentrations of densely packed …

The eye lens is a transparent and avascular organ in the front of the eye that is responsible
for focusing light onto the retina in order to transmit a clear image. A monolayer of epithelial …

Although the ocular lens shares many features with other tissues, it is unique in that it retains
its cells throughout life, making it ideal for studies of differentiation/development …

The short actin filaments in the red blood cell (RBC) membrane skeleton are capped at their
pointed ends by tropomodulin 1 (Tmod1) and coated with tropomyosin (TM) along their …

The eye and lens represent excellent models to understand embryonic development at
cellular and molecular levels. Initial 3D formation of the eye depends on a reciprocal …

High refractive index and transparency of the eye lens require uniformly shaped and
precisely aligned lens fiber cells. During lens development, equatorial epithelial cells …

Epithelial cells and differentiated fiber cells represent distinct compartments in the ocular
lens. While previous studies have revealed proteins that are preferentially expressed in …