COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

S Beyerstedt, EB Casaro, ÉB Rangel - European journal of clinical …, 2021 - Springer
COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …

Prognostic factors for severity and mortality in patients infected with COVID-19: A systematic review

A Izcovich, MA Ragusa, F Tortosa, MA Lavena Marzio… - PloS one, 2020 - journals.plos.org
Background and purpose The objective of our systematic review is to identify prognostic
factors that may be used in decision-making related to the care of patients infected with …

COVID-19: specific and non-specific clinical manifestations and symptoms: the current state of knowledge

J Baj, H Karakuła-Juchnowicz, G Teresiński… - Journal of clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19), due to the severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), has become an epidemiological threat and a worldwide …

COVID-19 and sex differences: mechanisms and biomarkers

T Haitao, JV Vermunt, J Abeykoon, R Ghamrawi… - Mayo Clinic …, 2020 - Elsevier
Men are consistently overrepresented in severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection, and coronavirus disease 2019 (COVID-19) severe outcomes …

Impact of cerebrovascular and cardiovascular diseases on mortality and severity of COVID-19–systematic review, meta-analysis, and meta-regression

R Pranata, I Huang, MA Lim… - Journal of stroke and …, 2020 - Elsevier
Background We conducted a systematic review and meta-analysis to evaluate the latest
evidence on the association between cerebrovascular, and cardiovascular diseases and …

COVID-19 and myocarditis: a systematic review and overview of current challenges

T Castiello, G Georgiopoulos, G Finocchiaro… - Heart failure …, 2022 - Springer
Myocardial inflammation in COVID-19 has been documented. Its pathogenesis is not fully
elucidated, but the two main theories foresee a direct role of ACE2 receptor and a …

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
Balanced immune regulation is crucial for recognizing an invading pathogen, its killing, and
elimination. Toll‐like receptors (TLRs) are the key regulators of the innate immune system. It …

Thrombotic complications of COVID-19

J Avila, B Long, D Holladay, M Gottlieb - The American journal of …, 2021 - Elsevier
Introduction The novel coronavirus disease of 2019 (COVID-19) is associated with
significant morbidity and mortality. The impact of thrombotic complications has been …

Coronavirus-induced myocarditis: a meta-summary of cases

JSY Ho, CH Sia, MYY Chan, W Lin, RCC Wong - Heart & Lung, 2020 - Elsevier
Background Myocarditis caused by SARS-CoV-2 infection was proposed to account for a
proportion of cardiac injury in patients with COVID-19. However, reports of coronavirus …

Myocardial injury in severe COVID-19 compared with non–COVID-19 acute respiratory distress syndrome

TS Metkus, LJ Sokoll, AS Barth, MJ Czarny, AG Hays… - Circulation, 2021 - Am Heart Assoc
Background: Knowledge gaps remain in the epidemiology and clinical implications of
myocardial injury in coronavirus disease 2019 (COVID-19). We aimed to determine the …