Role of microRNAs in the pathophysiology of addiction

AM Gowen, KE Odegaard, J Hernandez… - Wiley …, 2021 - Wiley Online Library
Addiction is a chronic and relapsing brain disorder characterized by compulsive seeking
despite adverse consequences. There are both heritable and epigenetic mechanisms …

EIF4A3-regulated circ_0087429 can reverse EMT and inhibit the progression of cervical cancer via miR-5003-3p-dependent upregulation of OGN expression

M Yang, H Hu, S Wu, J Ding, B Yin, B Huang… - Journal of Experimental …, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) are noncoding RNAs with stable structures
with high expression and tissue-specific expression. Studies have shown that circRNA …

Prognostic roles of ceRNA network-based signatures in gastrointestinal cancers

X Qi, X Chen, Y Zhao, J Chen, B Niu, B Shen - Frontiers in oncology, 2022 - frontiersin.org
Gastrointestinal cancers (GICs) are high-incidence malignant tumors that seriously threaten
human health around the world. Their complexity and heterogeneity make the classic …

[HTML][HTML] microRNA-132 regulates gene expression programs involved in microglial homeostasis

H Walgrave, A Penning, G Tosoni, S Snoeck, K Davie… - Iscience, 2023 - cell.com
Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

Large-scale inference of competing endogenous RNA networks with sparse partial correlation

M List, A Dehghani Amirabad, D Kostka… - …, 2019 - academic.oup.com
Motivation MicroRNAs (miRNAs) are important non-coding post-transcriptional regulators
that are involved in many biological processes and human diseases. Individual miRNAs …

LncRNA TTN‐AS1 acts as sponge for miR‐15b‐5p to regulate FBXW7 expression in ovarian cancer

S Miao, J Wang, L Xuan, X Liu - Biofactors, 2020 - Wiley Online Library
Emerging evidence showed that long noncoding RNA (lncRNA) plays crucial roles in
regulating various cancer biological behaviors. Titin‐antisense RNA1 (TTN‐AS1) has been …

Network approaches to study endogenous RNA competition and its impact on tissue-specific microRNA functions

TM Marques, M Gama-Carvalho - Biomolecules, 2022 - mdpi.com
microRNAs are small non-coding RNAs that play a key role in regulating gene expression.
These molecules exert their function through sequence complementarity with microRNA …

Integrated analysis of expression profiles with meat quality traits in cattle

Y Li, M Yang, A Lou, J Yun, C Ren, X Li, G Xia… - Scientific reports, 2022 - nature.com
MicroRNAs (miRNAs) play a vital role in improving meat quality by binding to messenger
RNAs (mRNAs). We performed an integrated analysis of miRNA and mRNA expression …

Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells

M Tarbier, SD Mackowiak, J Frade… - Nature …, 2020 - nature.com
Single-cell RNA sequencing studies on gene co-expression patterns could yield important
regulatory and functional insights, but have so far been limited by the confounding effects of …

From endogenous to synthetic microRNA-mediated regulatory circuits: An overview

E Ferro, C Enrico Bena, S Grigolon, C Bosia - Cells, 2019 - mdpi.com
MicroRNAs are short non-coding RNAs that are evolutionarily conserved and are pivotal
post-transcriptional mediators of gene regulation. Together with transcription factors and …