Microneedle-mediated vaccination: innovation and translation

T Sheng, B Luo, W Zhang, X Ge, J Yu, Y Zhang… - Advanced drug delivery …, 2021 - Elsevier
Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …

Approaches for enhancing oral bioavailability of peptides and proteins

J Renukuntla, AD Vadlapudi, A Patel… - International journal of …, 2013 - Elsevier
Oral delivery of peptide and protein drugs faces immense challenge partially due to the
gastrointestinal (GI) environment. In spite of considerable efforts by industrial and academic …

Transdermal microneedles for the programmable burst release of multiple vaccine payloads

KTM Tran, TD Gavitt, NJ Farrell, EJ Curry… - Nature Biomedical …, 2021 - nature.com
Repeated bolus injections are associated with higher costs and poor compliance and can
hinder the implementation of global immunization campaigns. Here, we report the …

[图书][B] Modern pharmaceutics

GS Banker, J Siepmann, C Rhodes - 2002 - books.google.com
" Completely revised and expanded throughout. Presents a comprehensive integrated,
sequenced approach to drug dosage formulation, design, and evaluation. Indentifies the …

Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach

A des Rieux, V Fievez, M Garinot, YJ Schneider… - Journal of controlled …, 2006 - Elsevier
Peptides and proteins remain poorly bioavailable upon oral administration. One of the most
promising strategies to improve their oral delivery relies on their association with colloidal …

Fabrication of fillable microparticles and other complex 3D microstructures

KJ McHugh, TD Nguyen, AR Linehan, D Yang… - Science, 2017 - science.org
Three-dimensional (3D) microstructures created by microfabrication and additive
manufacturing have demonstrated value across a number of fields, ranging from …

Peptide-functionalized liposomes as therapeutic and diagnostic tools for cancer treatment

JJ Sonju, A Dahal, SS Singh, SD Jois - Journal of Controlled Release, 2021 - Elsevier
Clinically efficacious medication in anticancer therapy has been successfully designed with
liposome-based nanomedicine. The liposomal formulation in cancer drug delivery can be …

Nanotechnology in vaccine delivery

LJ Peek, CR Middaugh, C Berkland - Advanced drug delivery reviews, 2008 - Elsevier
With very few adjuvants currently being used in marketed human vaccines, a critical need
exists for novel immunopotentiators and delivery vehicles capable of eliciting humoral …

Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D, L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent …

T Niwa, H Takeuchi, T Hino, N Kunou… - Journal of controlled …, 1993 - Elsevier
Nanospheres with d, l-lactide/glycolide copolymer (PLGA) were prepared as a
biodegradable polymeric carrier for both water-soluble and insoluble drugs by a novel …

Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery

L Brannon-Peppas - International journal of pharmaceutics, 1995 - Elsevier
The possibility of using biodegradable polymers as drug carriers was brought to the
attention of many scientists when bioresorbable sutures entered the market two decades …