Hematopoiesis during steady state conditions is regulated and finely tuned by a network of
cytokines and their effects on hematopoietic stem and progenitor cells and on accessory …

The recent discovery of thrombopoietin has enhanced our understanding of both
hematopoiesis and platelet production. Thrombopoietin supports hematopoietic stem cell …

Thrombopoietin (TPO) is a recently characterized member of the hematopoietic growth factor
family that serves as the primary regulator of megakaryocyte (MK) and platelet production …

The p53 protein has recently been reported to be capable of mediating apoptosis through a
pathway that is not dependent on its transactivation function. We report here that the PIASy …

The human c-mpl gene (MPL) plays an important role in the development of
megakaryocytes and platelets as well as the self-renewal of haematopoietic stem cells …

Opiates such as morphine or heroin may promote cell apoptosis and cause dysfunction of
immune cells. In simian immunodeficiency virus (SIV)-infected lymphocytic cells, however …

The pathobiological role of p53 has been widely studied, however, its role in
normophysiology is relatively unexplored. We previously showed that p53 knock-down …

Thrombopoietin (TPO) and its receptor (MPL) are important regulators of megakaryopoiesis.
MPL belongs to a cytokine receptor superfamily. To date, all constitutively active MPL …

Hair conditions, such as hair loss and graying, are prevalent human conditions. But they are
often poorly controlled due to our insufficient understanding of human scalp hair follicle …

Thrombopoietin (THPO), also known as megakaryocyte growth and development factor
(MGDF), is a cytokine involved in the production of platelets. THPO is a glycoprotein …