[HTML][HTML] Plasticity in neuroblastoma cell identity defines a noradrenergic-to-mesenchymal transition (NMT)
M Gautier, C Thirant, O Delattre, I Janoueix-Lerosey - Cancers, 2021 - mdpi.com
Simple Summary Neuroblastoma arises in the developing sympathetic nervous system and
represents the most common extracranial pediatric solid tumor. High-risk patients often …
represents the most common extracranial pediatric solid tumor. High-risk patients often …
[HTML][HTML] Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell
lines according to their epigenetic landscapes and core regulatory circuitries. However, their …
lines according to their epigenetic landscapes and core regulatory circuitries. However, their …
Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes
We performed collapsing analyses on 454,796 UK Biobank (UKB) exomes to detect gene-
level associations with diabetes. Recessive carriers of nonsynonymous variants in …
level associations with diabetes. Recessive carriers of nonsynonymous variants in …
Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
L Fanlo, S Gómez-González, C Rozalén… - Oncogene, 2023 - nature.com
Neuroblastoma is a pediatric cancer that can present as low-or high-risk tumors (LR-NBs
and HR-NBs), the latter group showing poor prognosis due to metastasis and strong …
and HR-NBs), the latter group showing poor prognosis due to metastasis and strong …
[HTML][HTML] An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression …
RH Chapple, X Liu, S Natarajan, MIM Alexander, Y Kim… - Genome Biology, 2024 - Springer
Background Neuroblastoma is a common pediatric cancer, where preclinical studies
suggest that a mesenchymal-like gene expression program contributes to chemotherapy …
suggest that a mesenchymal-like gene expression program contributes to chemotherapy …
Developmental Programs in Neuroblastoma
S Jansky, F Westermann - Neuroblastoma: Discoveries and Challenges, 2024 - Springer
Neuroblastoma is an embryonal tumor, which originates from the developing sympathetic
nervous system (Hoehner et al. Lab Investig 75: 659–75, 1996). Primary tumors frequently …
nervous system (Hoehner et al. Lab Investig 75: 659–75, 1996). Primary tumors frequently …
Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting metastasis
L Fanlo-Escudero, S Gómez-González, I Sangrador… - bioRxiv, 2021 - biorxiv.org
Neuroblastoma is a pediatric cancer that can present as low-or high-risk tumors (LR-NBs
and HR-NBs), the latter group showing poor prognosis due to metastasis and strong …
and HR-NBs), the latter group showing poor prognosis due to metastasis and strong …
[引用][C] Dr. in Polina Kameneva ist Researcher of the Month April 2022
K zeigt unsere Studie - Wien Klin Wochenschr, 2022 - Springer
MUW researcher of the month Page 1 MUW researcher of the month MUW researcher of the
month 1 3 332 Wien Klin Wochenschr (2022) 134:332–333 https:// doi.org/ 10.1007/ s00508 …
month 1 3 332 Wien Klin Wochenschr (2022) 134:332–333 https:// doi.org/ 10.1007/ s00508 …