Experimental studies that are relevant to human pregnancy rely on the selection of
appropriate animal models as an important element in experimental design. Consideration …

Abstract Over 30 years ago Professor David Barker first proposed the theory that events in
early life could explain an individual's risk of non‐communicable disease in later life: the …

There is a robust observational relationship between lower birthweight and higher risk of
cardiometabolic disease in later life. The Developmental Origins of Health and Disease …

Key points Inappropriate intake of key micronutrients in pregnancy is known to alter maternal
endocrine status, impair placental development and induce fetal growth restriction …

Key points Maternal exercise improves the metabolic health of maternal mice challenged
with a high‐fat diet. Exercise intervention of obese mothers prevents fetal overgrowth …

Depression is a prevalent condition affecting up to 20% of pregnant women. Hence, more
than 10% are prescribed antidepressant drugs, mainly serotonin reuptake inhibitors (SSRIs) …

Obesity is an increasing global health epidemic that affects all ages, including women of
reproductive age. During pregnancy, maternal obesity is associated with adverse pregnancy …

Key points Maternal obesity predisposes to metabolic dysfunction in male and female
offspring Maternal high‐fat diet consumption prior to and throughout pregnancy and …

Key points Obstructive sleep apnoea (OSA) is characterized by intermittent hypoxia, which
causes oxidative stress and inflammation and increases the risk of cardiovascular disease …

Maternal obesity is a global problem that increases the risk of short‐and long‐term adverse
outcomes for mother and child, many of which are linked to gestational diabetes mellitus …