The field of cancer genomics and transcriptomics has evolved from targeted profiling to swift
sequencing of individual tumor genome and transcriptome. The steady growth in genome …

DNA methylation is a fundamental epigenetic modification involved in various biological
processes and diseases. Analysis of DNA methylation data at a genome-wide and high …

Metastatic progression is a complex, multistep process and the leading cause of cancer
mortality. There is growing evidence that emphasises the significance of epigenetic …

Next-generation sequencing (NGS) studies have demonstrated that co-occurring sporadic
endometrioid endometrial carcinoma (EEC) and endometrioid ovarian carcinoma (EOC) are …

Background DNA methylation biomarkers are one of the most promising tools for the
diagnosis and differentiation of adenocarcinomas of the liver, which are among the most …

Globally, colorectal cancer (CRC) is the third most frequently occurring cancer. Progression
on to an advanced metastatic malignancy (metCRC) is often indicative of poor prognosis, as …

Sequencing-based genome-wide DNA methylation, gene expression studies and
associated data on paired colorectal cancer (CRC) primary and liver metastasis are very …

Aberrant DNA methylation is a universal feature of cancer. Here, we present a protocol for
generating high-quality genome-scale DNA methylation sequencing data from a variety of …

Simple Summary Contrary to the conventional understanding of DNA hypermethylation
suppressing gene expression, a new mechanism emerges, suggesting that high methylation …

Prostate cancer (PCa) is a major health burden worldwide, and despite early treatment,
many patients present with biochemical recurrence (BCR) post-treatment, reflected by a rise …