Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

Retinopathy of prematurity: a global perspective and recent developments

K Sabri, AL Ells, EY Lee, S Dutta, A Vinekar - Pediatrics, 2022 - publications.aap.org
Retinopathy of prematurity (ROP) is a significant cause of potentially preventable blindness
in preterm infants worldwide. It is a disease caused by abnormal retinal vascularization that …

Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled …

A Stahl, D Lepore, A Fielder, B Fleck, JD Reynolds… - The Lancet, 2019 - thelancet.com
Background Despite increasing worldwide use of anti-vascular endothelial growth factor
agents for treatment of retinopathy of prematurity (ROP), there are few data on their ocular …

Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)

ASH Tsai, HD Chou, XC Ling, T Al-Khaled… - Progress in retinal and …, 2022 - Elsevier
The incidence of retinopathy of prematurity (ROP) continues to rise due to the improved
survival of very low birth weight infants in developed countries. This epidemic is also fueled …

[HTML][HTML] A network meta-analysis of retreatment rates following bevacizumab, ranibizumab, aflibercept, and laser for retinopathy of prematurity

E Chang, AS Josan, R Purohit, CK Patel, K Xue - Ophthalmology, 2022 - Elsevier
Topic To compare bevacizumab, ranibizumab, aflibercept, and laser treatment as primary
therapies for retinopathy of prematurity (ROP) in terms of retreatment rate. Clinical relevance …

Pathophysiology, screening and treatment of ROP: a multi-disciplinary perspective

T Chan-Ling, GA Gole, GE Quinn, SJ Adamson… - Progress in retinal and …, 2018 - Elsevier
The population of infants at risk for retinopathy of prematurity (ROP) varies by world region;
in countries with well developed neonatal intensive care services, the highest risk infants are …

Comparing alternative ranibizumab dosages for safety and efficacy in retinopathy of prematurity: a randomized clinical trial

A Stahl, TU Krohne, N Eter, I Oberacher-Velten… - JAMA …, 2018 - jamanetwork.com
Importance Anti–vascular endothelial growth factor (VEGF) therapies are a novel treatment
option in retinopathy of prematurity (ROP). Data on dosing, efficacy, and safety are …

Follow-up to age 4 years of treatment of type 1 retinopathy of prematurity intravitreal bevacizumab injection versus laser: fluorescein angiographic findings

D Lepore, GE Quinn, F Molle, L Orazi, A Baldascino… - Ophthalmology, 2018 - Elsevier
Purpose To compare structural outcome at age 4 years of eyes treated with intravitreal
injection of bevacizumab with fellow eyes treated with conventional laser photoablation in …

A dosing study of bevacizumab for retinopathy of prematurity: late recurrences and additional treatments

DK Wallace, TW Dean, ME Hartnett, L Kong, LE Smith… - Ophthalmology, 2018 - Elsevier
Purpose Intravitreal bevacizumab is increasingly used to treat severe retinopathy of
prematurity (ROP), but it enters the bloodstream, and there is concern that it may alter …

Assessment of retinopathy of prematurity regression and reactivation using an artificial intelligence–based vascular severity score

SK Eilts, JM Pfeil, B Poschkamp, TU Krohne… - JAMA Network …, 2023 - jamanetwork.com
Importance One of the biggest challenges when using anti–vascular endothelial growth
factor (VEGF) agents to treat retinopathy of prematurity (ROP) is the need to perform long …