Secukinumab for the treatment of adult‐onset pityriasis rubra pilaris: a single‐arm clinical trial with transcriptomic analysis

BW Boudreaux, TP Pincelli, PK Bhullar… - British Journal of …, 2022 - academic.oup.com
Background The pathogenesis of pityriasis rubra pilaris (PRP) is not completely understood,
but interleukin (IL)‐17 has been shown to play a critical role. There are no reliable …

Pityriasis Rubra Pilaris: An Updated Review of Clinical Presentation, Etiopathogenesis, and Treatment Options

TP Joshi, M Duvic - American Journal of Clinical Dermatology, 2024 - Springer
Pityriasis rubra pilaris (PRP) is a rare papulosquamous reaction pattern with a significant
impact on quality of life. Type I PRP is the most common PRP variant, presenting as …

Evaluation of ixekizumab treatment for patients with pityriasis rubra pilaris: a single-arm trial

D Haynes, JL Strunck, CA Topham… - JAMA …, 2020 - jamanetwork.com
Importance Pityriasis rubra pilaris is a rare and disabling cutaneous disease that is
frequently recalcitrant to conventional therapies and appears to involve interleukin (IL)-17 …

[HTML][HTML] Emerging Role of Biologic Drugs Targeting IL-17 and IL-23: Pityriasis Rubra Pilaris

L Potestio, M D'Agostino, A Portarapillo, V Esposito… - Life, 2024 - mdpi.com
Pityriasis rubra pilaris (PRP) is a rare, papulosquamous, inflammatory skin disease. PRP
represents a therapeutic challenge. The rarity of this disease and its possible spontaneous …

[HTML][HTML] Pityriasis rubra pilaris response to IL-17A inhibition is associated with IL-17C and CCL20 protein levels

JL Strunck, B Cutler, B Rajpal, G Kent, D Haynes… - Journal of Investigative …, 2022 - Elsevier
Pityriasis rubra pilaris (PRP) is a rare, severe inflammatory skin disease associated with
high morbidity and debilitating effects on QOL (Eastham et al., 2019; Ross et al., 2016) …

[HTML][HTML] Pityriasis rubra pilaris following COVID-19 vaccination successfully treated with ixekizumab

P Zhao, CA Rusu, OL Schenck - JAAD Case Reports, 2023 - Elsevier
Pityriasis rubra pilaris (PRP) is a papulosquamous disorder of unknown etiology. Most cases
are sporadic, but there are also familial forms caused by mutations in the CARD14 gene. 1 …

Refractory Type I pityriasis rubra pilaris treated with tildrakizumab.

G Licata, A Gambardella, G Calabrese… - Clinical & …, 2021 - search.ebscohost.com
The patient had a history of chronic inflammatory bowel disease, thus excluding anti-
interleukin (IL)-17 therapy and he has also developed a needle phobia, thus excluding …

First onset of pityriasis rubra pilaris following SARS-CoV-2 booster vaccination: case report and review of the literature

T Gambichler, CH Scheel, Y Arafat, E Heinzer… - Dermato, 2022 - mdpi.com
There is increasing evidence of adverse events associated with the use of COVID-19
vaccines. Here, we report a case of the SARS-CoV-2-vaccination-related onset of pityriasis …

Response of pityriasis rubra pilaris to brodalumab after primary failure to ustekinumab.

V Amat‐Samaranch, X Cubiró… - International …, 2021 - search.ebscohost.com
Abstract Dear Editor, Pityriasis rubra pilaris (PRP) is a rare inflammatory dermatosis
characterized by keratotic follicular papules coalescing into scaly red-orange plaques. The …

Biologics for Treatment of Pityriasis Rubra Pilaris: A Literature Review

RJ Chandy, A Chokshi, I Tan… - Journal of Cutaneous …, 2024 - journals.sagepub.com
Objective: To describe the published efficacy and adverse event rates associated with
existing biologics for the treatment of pityriasis rubra pilaris (PRP). Data Sources: A literature …