It is now well accepted that many tumors undergo a process of clonal selection which means
that tumor antigens arising at various stages of tumor progression are likely to be …

Gene mutations can induce cellular alteration and malignant transformation. Development of
many types of cancer is associated with mutations in the B-raf proto-oncogene (BRAF) gene …

Purpose: Thyroid cancer cell lines are valuable models but have been neglected in
pancancer genomic studies. Moreover, their misidentification has been a significant …

Background Papillary thyroid cancer has been associated with chronic inflammation. A
systematic understanding of immune cell infiltration in PTC is essential for subsequent …

Purpose: To evaluate MHC class I expression on papillary thyroid cancer (PTC) and analyze
changes in MHC expression and associated immune activation with current and …

Anaplastic thyroid cancer (ATC) is a rare but fatal cancer with BRAF mutation ranging from
30 to 50%. Histone lysine lactylation represents a novel epigenetic mark that translates …

Background: There remain a small number of patients with papillary thyroid cancer (PTC)
who suffer recurrence, metastases, or death. While mutation of the BRAF gene …

The BRAF gene is commonly involved in normal processes of cell growth and differentiation.
The BRAF (V600E) mutation is found in several human cancer, causing an increase of cell …

Context: Thyroid nodules are common in adult population and papillary thyroid carcinoma
(PTC) is the most frequent malignant finding. The natural history of PTC remains poorly …

The tumor microenvironment heterogeneity of papillary thyroid cancer (PTC) is poorly
characterized. The relationship between PTC and Hashimoto thyroiditis (HT) is also in …