Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

Uncontrolled inflammation of the periodontal area may arise when complex microbial
communities transition from a commensal to a pathogenic entity. Communication among …

In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

Neutrophils have been historically associated with antimicrobial functions in acute infections
but are now appreciated as functionally versatile cells with critical roles in chronic …

The role of polymorphonuclear neutrophils (PMNs) in biology is often recognized during
pathogenesis associated with PMN hyper-or hypo-functionality in various disease states …

The human body supports the growth of a wide array of microbial communities in various
niches such as the oral cavity, gastro-intestinal and urogenital tracts, and on the surface of …

Once viewed as simply antibacterial effector cells packed with antimicrobials, neutrophils
are now increasingly appreciated for their regulatory roles in immunity and inflammation …

Although historically viewed as merely anti-microbial effectors in acute infection or injury,
neutrophils are now appreciated to be functionally versatile with critical roles also in chronic …

Periodontitis is one of the most common oral diseases resulting in gingival inflammation and
tooth loss. Growing evidence indicates that it results from dysbiosis of the oral microbiome …

Periodontitis is a prevalent inflammatory disease that leads to the destruction of the tooth-
supporting tissues. Current therapies are not effective for all patients and this oral disease …