Advanced glycation end products in the skin: Molecular mechanisms, methods of measurement, and inhibitory pathways

C Chen, JQ Zhang, L Li, M Guo, Y He, Y Dong… - Frontiers in …, 2022 - frontiersin.org
Advanced glycation end products (AGEs) are a series of stable compounds produced under
non-enzymatic conditions by the amino groups of biomacromolecules and the free carbonyl …

The central role of the NAD+ molecule in the development of aging and the prevention of chronic age-related diseases: strategies for NAD+ modulation

B Poljšak, V Kovač, S Špalj, I Milisav - International journal of molecular …, 2023 - mdpi.com
The molecule NAD+ is a coenzyme for enzymes catalyzing cellular redox reactions in
several metabolic pathways, encompassing glycolysis, TCA cycle, and oxidative …

miR-16-5p suppression protects human cardiomyocytes against endoplasmic reticulum and oxidative stress-induced injury

R Toro, A Pérez-Serra, A Mangas… - International Journal of …, 2022 - mdpi.com
Oxidative stress, defined as the excess production of reactive oxygen species (ROS) relative
to antioxidant defense, plays a significant role in the development of cardiovascular …

Lowered antioxidant defenses and increased oxidative toxicity are hallmarks of deficit schizophrenia: a nomothetic network psychiatry approach

M Maes, S Sirivichayakul, AK Matsumoto… - Molecular …, 2020 - Springer
There is now evidence that schizophrenia and deficit schizophrenia are neuro-immune
conditions and that oxidative stress toxicity (OSTOX) may play a pathophysiological role …

Skin Autofluorescence as a Potential Adjunctive Marker for Cardiovascular Risk Assessment in Type 2 Diabetes: A Systematic Review

D Reurean-Pintilei, A Pantea Stoian… - International Journal of …, 2024 - mdpi.com
Diabetes mellitus (DM), due to its long-term hyperglycemia, leads to the accumulation of
advanced glycation end-products (AGEs), especially in the vessel walls. Skin …

Understanding the role of glycation in the pathology of various non-communicable diseases along with novel therapeutic strategies

NS Bangar, A Gvalani, S Ahmad, MS Khan… - …, 2022 - academic.oup.com
Glycation refers to carbonyl group condensation of the reducing sugar with the free amino
group of protein, which forms Amadori products and advanced glycation end products …

Impact of time restricted feeding on markers of cardiometabolic health and oxidative stress in resistance-trained firefighters

MJ McAllister, AE Gonzalez… - The Journal of Strength & …, 2022 - journals.lww.com
Abstract McAllister, MJ, Gonzalez, AE, and Waldman, HS. Impact of time restricted feeding
on markers of cardiometabolic health and oxidative stress in resistance-trained firefighters. J …

Pleiotropic Properties of Valsartan: Do They Result from the Antiglycooxidant Activity? Literature Review and In Vitro Study

KM Mil, ME Gryciuk, C Pawlukianiec… - Oxidative Medicine …, 2021 - Wiley Online Library
Valsartan belongs to angiotensin II type 1 (AT1) receptor blockers (ARB) used in
cardiovascular diseases like heart failure and hypertension. Except for its AT1‐antagonism …

[HTML][HTML] Ca2+/Calmodulin-Dependent Protein Kinase II Regulation by Inhibitor of Receptor Interacting Protein Kinase 3 Alleviates Necroptosis in Glycation End …

Y Hua, J Qian, J Cao, X Wang, W Zhang… - International Journal of …, 2022 - mdpi.com
Necroptosisis a regulatory programmed form of necrosis. Receptor interacting protein kinase
3 (RIPK3) is a robust indicator of necroptosis. RIPK3 mediates myocardial necroptosis …

[HTML][HTML] Exercise, advanced glycation end products, and their effects on cardiovascular disorders: a narrative review

SH Hooshiar, H Esmaili, AM Taherian… - Heart and Mind, 2022 - journals.lww.com
Lifelong accumulation of advanced glycation end products (AGEs) is linked to
cardiovascular disease (CVD). As a result of AGEs, cardiovascular dysfunction develops …