Fluorinated analogues of the canonical α-L-amino acids have gained widespread attention
as building blocks that may endow peptides and proteins with advantageous biophysical …

Residue-specific incorporation of non-canonical amino acids into proteins allows facile
alteration and enhancement of protein properties. In this review, we describe recent …

Marine invertebrates are rich sources of bioactive compounds and their biotechnological
potential attracts scientific and economic interest worldwide. Although sponges are the …

Biomaterials produced by nature have been honed through billions of years, evolving
exquisitely precise structure–function relationships that scientists strive to emulate …

Despite their diverse functions, proteins are inherently constructed from a limited set of
building blocks. These compositional constraints pose significant challenges to protein …

Traditionally, the biological fluorination of complex biological systems like proteins is
achieved through substitution of canonical amino acids or addition of fluorinated amino …

Red fluorescent proteins (RFPs) represent an increasingly popular class of genetically
encodable bioprobes and biomarkers that can advance next‐generation breakthroughs …

A family of versatile promoter-probe plasmids for gene expression analysis was developed
based on a modular expression plasmid system (pZ). The vectors contain different replicons …

In this comprehensive review, I focus on the twenty E. coli aminoacyl‐tRNA synthetases and
their ability to charge non‐canonical amino acids (ncAAs) onto tRNAs. The promiscuity of …

We describe the simple bioconjugation strategy in combination of periodate chemistry and
unnatural amino acid incorporation. The residue specific incorporation of 3, 4-dihydroxy-l …