TERC haploid cell reprogramming: a novel therapeutic strategy for aplastic anemia

X Tang, R Xu, Y Wang, K Chen, S Cui - Molecular Medicine, 2023 - Springer
The telomerase RNA component (TERC) gene plays an important role in telomerase-
dependent extension and maintenance of the telomeres. In the event of TERC …

Current concepts of the pathogenesis of aplastic anemia

C Liu, Y Sun, Z Shao - Current pharmaceutical design, 2019 - ingentaconnect.com
Abnormal activation of the immune system plays an important role in the pathogenesis of
aplastic anemia (AA). Various immune cells and cytokines constitute a complex immune …

The cross talk between type II diabetic microenvironment and the regenerative capacities of human adipose tissue-derived pericytes: a promising cell therapy

TA Ahmed, SM Ahmed, H Elkhenany… - Stem Cell Research & …, 2024 - Springer
Abstract Background Pericytes (PCs) are multipotent contractile cells that wrap around the
endothelial cells (ECs) to maintain the blood vessel's functionality and integrity. The …

[HTML][HTML] MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence

T Li, Z Luo, S Lin, C Li, S Dai, H Wang, J Huang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Abstract Protection of telomere 1 (POT1), the telomeric single-stranded DNA (ssDNA)-
binding protein in the shelterin complex, has been implicated in the DNA damage response …

Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component …

L Spano, C Marie-Claire, O Godin, A Lebras… - Translational …, 2024 - nature.com
Bipolar disorder (BD) has been associated with premature cellular aging with shortened
telomere length (TL) as compared to the general population. We recently identified a …

Associations between the HLA-A/B/DRB1 polymorphisms and aplastic anemia: evidence from 17 case–control studies

XZ Deng, M Du, J Peng, JX Long, CJ Zheng, Y Tan… - …, 2018 - Taylor & Francis
Objective: To estimate the associations between HLA-A/B/DRB1 polymorphisms and
aplastic anemia (AA), we carried out the meta-analysis. Methods: In this meta-analysis, all …

Aplastic anemia in China

C Liu, Z Shao - Journal of Translational Internal Medicine, 2018 - degruyter.com
Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia. Up to now,
severe aplastic anemia (SAA) has been recognized by international and domestic scholars …

[HTML][HTML] The shortening telomere length of T lymphocytes maybe associated with hyper‑function in servere aplastic anemia

C Wang, T Zhang, Y Wang, Y Li… - Molecular …, 2018 - spandidos-publications.com
Severe aplastic anemia (SAA) is a primary disorder of severe bone marrow failure
characterizing with extreme pancytopenia and a profound diminution of bone marrow …

Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and …

P Saxena, J Srivastava, B Rai, NK Tripathy… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Bone marrow mesenchymal stem cells (BM-MSC) are an integral part of the BM
niche that is essential to maintain hematopoietic homeostasis. In aplastic anemia (AA), a few …

[HTML][HTML] 再生障碍性贫血发病机制的研究进展

杨洁茹, 王化泉, 邵宗鸿 - Chinese Journal of Hematology, 2019 - ncbi.nlm.nih.gov
再生障碍性贫血发病机制的研究进展- PMC Back to Top Skip to main content NIH NLM Logo
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