Phosphatidate-mediated regulation of lipid synthesis at the nuclear/endoplasmic reticulum membrane

JM Kwiatek, GS Han, GM Carman - … Acta (BBA)-Molecular and Cell Biology …, 2020 - Elsevier
In yeast and higher eukaryotes, phospholipids and triacylglycerol are derived from
phosphatidate at the nuclear/endoplasmic reticulum membrane. In de novo biosynthetic …

Fat-regulating phosphatidic acid phosphatase: a review of its roles and regulation in lipid homeostasis

GM Carman, GS Han - Journal of lipid research, 2019 - ASBMB
Phosphatidic acid (PA) phosphatase is an evolutionarily conserved enzyme that plays a
major role in lipid homeostasis by controlling the cellular levels of its substrate, PA, and its …

Combined CdS nanoparticles-assisted photocatalysis and periphytic biological processes for nitrate removal

N Zhu, J Tang, C Tang, P Duan, L Yao, Y Wu… - Chemical Engineering …, 2018 - Elsevier
The concept of improving in-situ nitrate removal was demonstrated in a CdS nanoparticles
(NPs)-assisted periphyton bioelectrochemical system (PCdS-BES). Compared to the control …

The MoPah1 phosphatidate phosphatase is involved in lipid metabolism, development, and pathogenesis in Magnaporthe oryzae

J Zhao, P Sun, Q Sun, R Li, Z Qin, G Sha… - Molecular Plant …, 2022 - Wiley Online Library
As with the majority of the hemibiotrophic fungal pathogens, the rice blast fungus
Magnaporthe oryzae uses highly specialized infection structures called appressoria for plant …

Time-delayed photocatalysis enhanced microbial nitrate reduction via solar energy storage in carbon nitrides

X Zhou, C Zhang, Y Li - Chemical Engineering Journal, 2021 - Elsevier
The increase in nitrogen, especially nitrate, in the water environment poses a great threat to
human health and makes the need to develop ways to efficiently remove nitrate from water …

[HTML][HTML] pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity

MA Deprez, E Eskes, T Wilms, P Ludovico… - Microbial …, 2018 - ncbi.nlm.nih.gov
The plasma membrane H+-ATPase Pma1 and the vacuolar V-ATPase act in close harmony
to tightly control pH homeostasis, which is essential for a vast number of physiological …

A novel simultaneous coupling of memory photocatalysts and microbial communities for alternate removal of dimethyl phthalate and nitrate in water under light/dark …

X Zhou, W Xiong, Y Li, C Zhang, X Xiong - Journal of Hazardous Materials, 2022 - Elsevier
Efficient and sustainable removal of both organic and inorganic pollutants from
contaminated water is an important but difficult task. Here, a novel chemical-biological …

The endosomal network: mediators and regulators of endosome maturation

M Podinovskaia, A Spang - Endocytosis and Signaling, 2018 - Springer
Endocytosis is a means for the cell to sample its environment for nutrients and regulate
plasma membrane (PM) composition and area. Whereas the majority of internalized cargo is …

Mutant phosphatidate phosphatase Pah1-W637A exhibits altered phosphorylation, membrane association, and enzyme function in yeast

Y Park, GJ Stukey, R Jog, JM Kwiatek, GS Han… - Journal of Biological …, 2022 - ASBMB
The Saccharomyces cerevisiae PAH1-encoded phosphatidate (PA) phosphatase, which
catalyzes the dephosphorylation of PA to produce diacylglycerol, controls the bifurcation of …

Conserved regions of the regulatory subunit Spo7 are required for Nem1–Spo7/Pah1 phosphatase cascade function in yeast lipid synthesis

R Jog, GS Han, GM Carman - Journal of Biological Chemistry, 2023 - ASBMB
In the yeast Saccharomyces cerevisiae, the Nem1–Spo7 complex is a protein phosphatase
that activates Pah1 phosphatidate phosphatase at the nuclear–endoplasmic reticulum …