The problem of inadequate statistical reporting is long standing and widespread in the biomedical literature, including in cardiovascular physiology. Although guidelines for …
Voltage dependent anion channel 2 (VDAC2) is an outer mitochondrial membrane porin known to play a significant role in apoptosis and calcium signaling. Abnormalities in calcium …
Á Kovács, M Herwig, H Budde, S Delalat, D Kolijn… - Antioxidants, 2021 - mdpi.com
Standard heart failure (HF) therapies have failed to improve cardiac function or survival in HF patients with right ventricular (RV) dysfunction suggesting a divergence in the molecular …
D Si, MA Azam, PFH Lai, N Zamiri… - Journal of …, 2018 - Wiley Online Library
Introduction Following long‐duration ventricular fibrillation (LDVF), reinitiation of ventricular fibrillation (VF) poses a major challenge during resuscitation. Ryanodine receptor 2 (RyR2) …
X Chen, C Zhang, Y Guo, X Liu, T Ye, Y Fo, C Qu… - Life Sciences, 2020 - Elsevier
Aim The purpose of the study was to investigate what effects the sigma-1 receptor (S1R) could exert on the cardiac myocyte ion channels in a rodent model of depression and to …
X Sun, J Cao, Z Chen, Y Liu, JL VonCannon, HJ Cheng… - Heliyon, 2023 - cell.com
Abstract Aims Upregulation of Ca 2+/calmodulin-dependent protein kinase II (CaMKII) contributes to the pathogenesis of cardiovascular disease, including hypertension …
AV Zaitsev, NS Torres, KM Cawley… - American Journal …, 2019 - journals.physiology.org
The “stress” kinases cAMP-dependent protein kinase (PKA) and calcium/calmodulin- dependent protein kinase II (CaMKII), phosphorylate the Na+ channel Nav1. 5 subunit to …
K Ma, G Ma, Z Guo, G Liu… - Experimental and …, 2021 - spandidos-publications.com
Ventricular arrhythmia (VA) is a highly fatal arrhythmia that involves multiple ion channels. Of all sudden cardiac death events,~ 85% result from VAs, including ventricular tachycardia …
M Warren, AV Zaitsev - Cardiovascular Research, 2017 - academic.oup.com
We have read the study by Takanari et al. 1 published in Cardiovascular Research with interest, all the more so given that the reported results are in stark contrast with our own …