Persistent diabetic macular edema: Definition, incidence, biomarkers, and treatment methods

OA Sorour, ES Levine, CR Baumal, AG Elnahry… - Survey of …, 2023 - Elsevier
Intravitreal antivascular endothelial growth factor (anti-VEGF) treatment has drastically
improved the visual and anatomical outcomes in patients with diabetic macular edema …

The role of steroids in the management of diabetic macular edema

D Zur, M Iglicki, A Loewenstein - Ophthalmic Research, 2019 - karger.com
Inflammation is substantially contributing to the development and worsening of diabetic
retinopathy in general and diabetic macular edema (DME) in particular, which provides the …

Disorganization of retinal inner layers as a biomarker in patients with diabetic macular oedema treated with dexamethasone implant

D Zur, M Iglicki, A Sala‐Puigdollers… - Acta …, 2020 - Wiley Online Library
Purpose To investigate disorganization of retinal inner layers (DRIL) as a biomarker in eyes
with diabetic macular oedema (DME) treated by intravitreal dexamethasone (DEX) implant …

Current treatments for diabetic macular edema

T Tatsumi - International Journal of Molecular Sciences, 2023 - mdpi.com
Diabetic retinopathy is a major retinal disorder and a leading cause of blindness. Diabetic
macular edema (DME) is an ocular complication in patients with diabetes, and it can impair …

Intravitreal therapy for diabetic macular edema: an update

C Furino, F Boscia, M Reibaldi… - Journal of …, 2021 - Wiley Online Library
Diabetic macular edema (DME) represents a prevalent and disabling eye condition. Despite
that DME represents a sight‐threatening condition, it is also among the most accessible to …

The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases

T Van Bergen, I Etienne, F Cunningham… - Progress in retinal and …, 2019 - Elsevier
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF)
family. Upon binding to VEGF-and neuropilin-receptor sub-types, PlGF modulates a range of …

Fluocinolone acetonide implant in diabetic macular edema: International experts' panel consensus guidelines and treatment algorithm

L Kodjikian, F Bandello, M De Smet… - European Journal …, 2022 - journals.sagepub.com
Center-involving diabetic macular edema (DME) is a leading cause of vision impairment in
working-age adults. While its management is particularly challenging in a poorly compliant …

[HTML][HTML] A collaborative retrospective study on the efficacy and safety of intravitreal dexamethasone implant (Ozurdex) in patients with diabetic macular edema: the …

A Rosenblatt, P Udaondo, J Cunha-Vaz, S Sivaprasad… - Ophthalmology, 2020 - Elsevier
Purpose To evaluate the efficacy, effect profile, and safety of dexamethasone implant on
diabetic macular edema (DME) in a real-life setting, further comparing results by DME …

[HTML][HTML] New insights in resistant diabetic macular edema

DAK Kuroiwa, FK Malerbi, CVS Regatieri - Ophthalmologica, 2021 - karger.com
Diabetic macular edema (DME) is the most common cause of vision loss in diabetic eyes,
and due to the rapid rise in the number of diabetic patients, the treatment burden has …

Real-world outcomes of non-responding diabetic macular edema treated with continued anti-VEGF therapy versus early switch to dexamethasone implant: 2-year …

C Busch, S Fraser-Bell, M Iglicki, M Lupidi… - Acta …, 2019 - Springer
Aims To provide 2-year follow-up data on eyes with diabetic macular edema (DME) that
were non-responsive after three initial anti-vascular endothelial growth factor (VEGF) …