[HTML][HTML] Diabetic muscular atrophy: molecular mechanisms and promising therapies

Y Shen, M Li, K Wang, G Qi, H Liu, W Wang… - Frontiers in …, 2022 - frontiersin.org
Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types,
dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications …

[HTML][HTML] Current strategies in assessment of nanotoxicity: alternatives to in vivo animal testing

HJ Huang, YH Lee, YH Hsu, CT Liao, YF Lin… - International journal of …, 2021 - mdpi.com
Millions of experimental animals are widely used in the assessment of toxicological or
biological effects of manufactured nanomaterials in medical technology. However, the …

[HTML][HTML] Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage …

Y Liu, J Chen, H Liang, Y Cai, X Li, L Yan… - Stem cell research & …, 2022 - Springer
Background Endothelial damage is an initial step of macro-and micro-vasculature
dysfunctions in diabetic patients, accounting for a high incidence of diabetic vascular …

Adipose-derived mesenchymal stem cells therapy as a new treatment option for diabetes mellitus

A Mikłosz, A Chabowski - The Journal of Clinical Endocrinology …, 2023 - academic.oup.com
The worldwide increase in the prevalence of diabetes mellitus has raised the demand for
new therapeutic strategies targeting diabetic symptoms and its chronic complications …

[HTML][HTML] Revisiting the advances in isolation, characterization and secretome of adipose-derived stromal/stem cells

NK Dubey, VK Mishra, R Dubey, YH Deng… - International journal of …, 2018 - mdpi.com
Adipose-derived stromal/stem cells (ASCs) seems to be a promising regenerative
therapeutic agent due to the minimally invasive approach of their harvest and multi-lineage …

Mesenchymal stem cell-derived extracellular vesicle-based therapies protect against coupled degeneration of the central nervous and vascular systems in stroke

A Rahmani, K Saleki, N Javanmehr… - Ageing research …, 2020 - Elsevier
Stem cell-based treatments have been suggested as promising candidates for stroke.
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …

[HTML][HTML] Smart polymers for cell therapy and precision medicine

HJ Huang, YL Tsai, SH Lin, S Hsu - Journal of biomedical science, 2019 - Springer
Soft materials have been developed very rapidly in the biomedical field over the past 10
years because of advances in medical devices, cell therapy, and 3D printing for precision …

SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy

E Torre, M Arici, AM Lodrini, M Ferrandi… - Cardiovascular …, 2022 - academic.oup.com
Aims Diabetic cardiomyopathy is a multifactorial disease characterized by an early onset of
diastolic dysfunction (DD) that precedes the development of systolic impairment …

Extracellular vesicles from adipose-derived stem cells promote diabetic wound healing via the PI3K-AKT-mTOR-HIF-1α signaling pathway

W Liu, Y Yuan, D Liu - Tissue Engineering and Regenerative Medicine, 2021 - Springer
Background: Impaired potential of hypoxia-mediated angiogenesis lead poor healing of
diabetic wounds. Previous studies have shown that extracellular vesicles from adipose …

[HTML][HTML] The clinical efficacy and safety of stem cell therapy for diabetes mellitus: a systematic review and meta-analysis

Y Zhang, W Chen, B Feng, H Cao - Aging and disease, 2020 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a chronic metabolic disease with high morbidity and mortality.
Recently, stem cell-based therapy for DM has shown considerable promise. Here, we …