Effects and mechanisms of natural plant active compounds for the treatment of osteoclast-mediated bone destructive diseases
Q Xu, Z Cao, JQ Xu, M Dai, B Zhang, Q Lai… - Journal of Drug …, 2022 - Taylor & Francis
Bone-destructive diseases, caused by overdifferentiation of osteoclasts, reduce bone mass
and quality, and disrupt bone microstructure, thereby causes osteoporosis, Paget's disease …
and quality, and disrupt bone microstructure, thereby causes osteoporosis, Paget's disease …
Decursin and decursinol angelate: molecular mechanism and therapeutic potential in inflammatory diseases
Epidemiological studies have shown that inflammation plays a critical role in the
development and progression of various chronic diseases, including cancers, neurological …
development and progression of various chronic diseases, including cancers, neurological …
Potent inhibition of monoamine oxidase A by decursin from Angelica gigas Nakai and by wogonin from Scutellaria baicalensis Georgi
HW Lee, HW Ryu, MG Kang, D Park, H Lee… - International journal of …, 2017 - Elsevier
During the ongoing search for new monoamine oxidase (MAO) inhibitors, five coumarin
derivatives and eight flavonoids were isolated from the roots of Angelica gigas Nakai and …
derivatives and eight flavonoids were isolated from the roots of Angelica gigas Nakai and …
RETRACTED ARTICLE: Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis
Postmenopausal osteoporosis (POMP) is a public health problem characterized by
decreased bone density and increased fracture risk. Over-activated osteoclastogenesis …
decreased bone density and increased fracture risk. Over-activated osteoclastogenesis …
[HTML][HTML] Pain Relief, Functional Recovery, and Chondroprotective Effects of Angelica gigas Nakai in Osteoarthritis Due to Its Anti-Inflammatory Property: An In Vitro …
HG Jo, CY Baek, Y Hwang, E Baek, HS Song, D Lee - Nutrients, 2024 - mdpi.com
Osteoarthritis (OA), characterized by chronic pain and joint degradation, is a progressive
joint disease primarily induced by age-related systemic inflammation. Angelica gigas Nakai …
joint disease primarily induced by age-related systemic inflammation. Angelica gigas Nakai …
Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation
N Du, L Song, Y Li, T Wang, Q Fang, J Ou… - International …, 2020 - Elsevier
Based on previous studies, we know that estrogen can protect the joints from arthritis
development by increasing IgG glycosylation and inhibiting osteoclast activation …
development by increasing IgG glycosylation and inhibiting osteoclast activation …
Anti-cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells
SH Kim, SW Lee, HJ Park, SH Lee, WK Im… - … and alternative medicine, 2018 - Springer
Background The polysaccharide component of Angelica gigas induces immuno-stimulatory
effects on innate immune cells. However, it is unclear whether A. gigas' adjuvant activity on …
effects on innate immune cells. However, it is unclear whether A. gigas' adjuvant activity on …
Effects of interleukin‐7/interleukin‐7 receptor on RANKL‐mediated osteoclast differentiation and ovariectomy‐induced bone loss by regulating c‐Fos/c‐Jun pathway
JJ Zhao, ZF Wu, YH Yu, L Wang… - Journal of cellular …, 2018 - Wiley Online Library
To explore the effects of IL‐7/IL‐7R on the RANKL‐mediated osteoclast differentiation in
vitro and OVX‐induced bone loss in vivo. BMMs and RAW264. 7 were transfected with IL‐7 …
vitro and OVX‐induced bone loss in vivo. BMMs and RAW264. 7 were transfected with IL‐7 …
Angelica gigas: Signature Compounds, In Vivo Anticancer, Analgesic, Neuroprotective and Other Activities, and the Clinical Translation Challenges
Angelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in
Korea. AGN root ethanolic extract dietary supplements are marketed in the United States for …
Korea. AGN root ethanolic extract dietary supplements are marketed in the United States for …
Effect of essential oil and supercritical carbon dioxide extract from the root of Angelica gigas on human EEG activity
Objectives The present study aimed to investigate the effect of inhalation of essential oil (EO)
and supercritical carbon dioxide extract (SC-CO 2) from the root of A. gigas on human …
and supercritical carbon dioxide extract (SC-CO 2) from the root of A. gigas on human …