From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2024 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

LncRNA MALAT1-related signaling pathways in osteosarcoma

M Farzaneh, S Najafi, O Anbiyaee, S Azizidoost… - Clinical and …, 2023 - Springer
Osteosarcoma (OS) is a common and malignant form of bone cancer, which affects children
and young adults. OS is identified by osteogenic differentiation and metastasis. However …

[HTML][HTML] STAT3 signaling in prostate cancer progression and therapy resistance: An oncogenic pathway with diverse functions

M Sadrkhanloo, MDA Paskeh, M Hashemi… - Biomedicine & …, 2023 - Elsevier
The categorization of cancers demonstrates that prostate cancer is the most common
malignancy in men and it causes high death annually. Prostate cancer patients are …

The functions of long non-coding RNA (lncRNA)-MALAT-1 in the pathogenesis of renal cell carcinoma

O Anbiyaee, A Moalemnia, F Ghaedrahmati… - BMC nephrology, 2023 - Springer
Renal cell carcinoma (RCC), a prevalent form of renal malignancy, is distinguished by its
proclivity for robust tumor proliferation and metastatic dissemination. Long non-coding RNAs …

MALAT1 participates in the role of platelet-rich plasma exosomes in promoting wound healing of diabetic foot ulcer

C Chen, Q Wang, D Li, Z Qi, Y Chen, S Wang - International Journal of …, 2023 - Elsevier
Exosomes isolated from platelet-rich plasma (PRP-exos) have been recently deemed as an
optimized therapeutic strategy in diabetic foot ulcer (DFU) treatment. Herein, we aimed to …

Emerging role of exosome-derived non-coding RNAs in tumor-associated angiogenesis of tumor microenvironment

SL Duan, WJ Fu, YK Jiang, LS Peng… - Frontiers in Molecular …, 2023 - frontiersin.org
The tumor microenvironment (TME) is an intricate ecosystem that is actively involved in
various stages of cancer occurrence and development. Some characteristics of tumor …

The regulatory activities of MALAT1 in the development of bone and cartilage diseases

D Zhang, J Xue, F Peng - Frontiers in Endocrinology, 2022 - frontiersin.org
Long non-coding RNAs (lncRNAs) have been comprehensively implicated in various
cellular functions by mediating transcriptional or post-transcriptional activities. MALAT1 is …

Programmable ligation-transcription circuit-driven cascade amplification machinery for multiple long noncoding RNAs detection in lung tissues

Y Zhang, X Du, W Liu, M Liu, C Zhang - Analytical Chemistry, 2022 - ACS Publications
The measurement of long noncoding RNAs (lncRNAs) is essential to diagnosis and
treatment of various diseases such as cancers. Herein, we develop a simple method to …

METTL3 mediated MALAT1 m6A modification promotes proliferation and metastasis in osteosarcoma cells

Y Zhang, Y Xu, G Qiu, Y Luo, Y Bao, J Lu, T Wang… - Molecular …, 2024 - Springer
Background As one of the most ubiquitous types of posttranscriptional modification, N6-
methyladenosine (m6A) is extensively implicated in almost all types of cancers, including …

Downregulation of MALAT1 is a hallmark of tissue and peripheral proliferative T cells in COVID-19

S Dey, H Ashwin, L Milross, B Hunter… - Clinical and …, 2023 - academic.oup.com
T cells play key protective but also pathogenic roles in COVID-19. We studied the
expression of long non-coding RNAs (lncRNAs) in COVID-19 T-cell transcriptomes by …