The future of rodent models in depression research

A Gururajan, A Reif, JF Cryan, DA Slattery - Nature Reviews …, 2019 - nature.com
Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …

Neurobiological interactions between stress and the endocannabinoid system

M Morena, S Patel, JS Bains, MN Hill - Neuropsychopharmacology, 2016 - nature.com
Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

[HTML][HTML] Virtual reality is sexist: but it does not have to be

K Stanney, C Fidopiastis, L Foster - Frontiers in Robotics and AI, 2020 - frontiersin.org
The aim of this study was to assess what drives gender-based differences in the experience
of cybersickness within virtual environments. In general, those who have studied …

Stress and the social brain: behavioural effects and neurobiological mechanisms

C Sandi, J Haller - Nature reviews neuroscience, 2015 - nature.com
Stress often affects our social lives. When undergoing high-level or persistent stress,
individuals frequently retract from social interactions and become irritable and hostile …

Stress and cognition

C Sandi - Wiley Interdisciplinary Reviews: Cognitive Science, 2013 - Wiley Online Library
Stress can affect cognition in many ways, with the outcome (ie, facilitating or impairing)
depending on a combination of factors related to both stress and the cognitive function …

[HTML][HTML] High anxiety trait: a vulnerable phenotype for stress-induced depression

M Weger, C Sandi - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
A great deal of research aims to identify risk factors related to individual vulnerability to
develop stress-induced psychopathologies. Here, we summarize evidence that point at …

Sex differences in anxiety and emotional behavior

NC Donner, CA Lowry - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
Research has elucidated causal links between stress exposure and the development of
anxiety disorders, but due to the limited use of female or sex-comparative animal models …

Neurobiology of chronic mild stress: parallels to major depression

MN Hill, KGC Hellemans, P Verma, BB Gorzalka… - Neuroscience & …, 2012 - Elsevier
The chronic mild (or unpredictable/variable) stress (CMS) model was developed as an
animal model of depression more than 20 years ago. The foundation of this model was that …

Stress hormone regulation: biological role and translation into therapy

F Holsboer, M Ising - Annual review of psychology, 2010 - annualreviews.org
Stress is defined as a state of perturbed homeostasis following endangerment that evokes
manifold adaptive reactions, which are summarized as the stress response. In the case of …

Endocannabinoid system, stress and HPA axis

V Micale, F Drago - European journal of pharmacology, 2018 - Elsevier
The endocannabinoid system (ECS), which is composed of the cannabinoid receptors types
1 and 2 (CB1 and CB2) for marijuana's psychoactive ingredient∆ 9-tetrahydrocannabinol (∆ …