Tempol is a redox-cycling nitroxide that promotes the metabolism of many reactive oxygen
species (ROS) and improves nitric oxide bioavailability. It has been studied extensively in …

Sun exposure has been linked to several types of skin damage including sun burn,
photoimmunosuppression, photoaging and photocarcinogenesis. In view of the increasing …

Ultraviolet radiation damage to the skin is due, in part, to the generation of reactive oxygen
species. Vitamin C (l‐ascorbic acid) functions as a biological co‐factor and antioxidant due …

A comprehensive comparison of antioxidant defenses in the dermis and epidermis and their
response to exposure to ultraviolet (UV) irradiation has not previously been attempted. In …

Chronic exposure of solar ultraviolet (UV) light to human skin results in photoaging. UV-
induced oxidative damage and induction of matrix metalloproteinases (MMP) have been …

The degree to which antioxidant loss occurs in human skin after UV irradiation is unknown,
as is the cascade of events that might occur. We have, therefore, evaluated a tissue culture …

There has not as yet been an integrated, comprehensive study of the responses of dermis
and epidermis in vivo to a wide range of ultraviolet (UV) doses, encompassing all major …

8-Hydroxy-2'-deoxyguanosine (8-OhdG) is a mutation-prone (G: C to T: A tranversion) DNA
base-modified product generated by reactive oxygen species or photodynamic action. G: C …

The aim of this study was to investigate the effects of topical α‐tocopherol application on
epidermal and dermal antioxidants and its ability to prevent ultraviolet (UV)‐induced …

Objectives: This study addressed whether food and nutrient intakes were correlated with
skin wrinkling in a sun-exposed site. Methods: 177 Greek-born subjects living in Melbourne …