Located between vessels of the choriocapillaris and light-sensitive outer segments of the
photoreceptors, the retinal pigment epithelium (RPE) closely interacts with photoreceptors in …

Our understanding of endocytosis has evolved remarkably in little more than a decade. This
is the result not only of advances in our knowledge of its molecular and biological workings …

Usher syndrome (USH) is the most frequent cause of combined deaf-blindness in man. It is
clinically and genetically heterogeneous and at least 12 chromosomal loci are assigned to …

Recessive splice site and nonsense mutations of PCDH15, encoding protocadherin 15, are
known to cause deafness and retinitis pigmentosa in Usher syndrome type 1F (USH1F) …

Usher syndrome type IIA (USH2A), characterized by progressive photoreceptor
degeneration and congenital moderate hearing loss, is the most common subtype of Usher …

Usher syndrome (USH) is an autosomal recessive disease characterized by hearing loss,
retinitis pigmentosa (RP), and, in some cases, vestibular dysfunction. It is clinically and …

Usher syndrome is the most common form of deaf-blindness. The syndrome is both clinically
and genetically heterogeneous, and to date, eight causative genes have been identified …

The human Usher syndrome (USH) is the most frequent cause of combined deaf–blindness.
USH is genetically heterogeneous with at least 12 chromosomal loci assigned to three …

The USH2A gene is mutated in patients with Usher syndrome type IIa, which is the most
common subtype of Usher syndrome and is characterized by hearing loss and retinitis …

Sensorineural hearing loss is a common and currently irreversible disorder, because
mammalian hair cells (HCs) do not regenerate and current stem cell and gene delivery …