Cyanobacteria are the globally dominant photoautotrophic lineage. Their success is dependent on a set of adaptations collectively termed the CO2-concentrating mechanism …
We describe a general computational method for designing proteins that self-assemble to a desired symmetric architecture. Protein building blocks are docked together symmetrically to …
Cancers that appear pathologically similar often respond differently to the same drug regimens. Methods to better match patients to drugs are in high demand. We demonstrate a …
Bacterial microcompartments (BMCs) are proteinaceous organelles involved in both autotrophic and heterotrophic metabolism. All BMCs share homologous shell proteins but …
C Chowdhury, S Sinha, S Chun… - Microbiology and …, 2014 - Am Soc Microbiol
Bacterial microcompartments (MCPs) are sophisticated protein-based organelles used to optimize metabolic pathways. They consist of metabolic enzymes encapsulated within a …
MJ Lee, J Mantell, L Hodgson, D Alibhai… - Nature chemical …, 2018 - nature.com
We have developed a system for producing a supramolecular scaffold that permeates the entire Escherichia coli cytoplasm. This cytoscaffold is constructed from a three-component …
Targeting of proteins to bacterial microcompartments (BMCs) is mediated by an 18-amino- acid peptide sequence. Herein, we report the solution structure of the N-terminal targeting …
Bacterial microcompartments (BMCs) are protein-bound organelles predicted to be present across 23 bacterial phyla. BMCs facilitate carbon fixation as well as the aerobic and …
C Chowdhury, S Chun, A Pang… - Proceedings of the …, 2015 - National Acad Sciences
Bacterial microcompartments are widespread prokaryotic organelles that have important and diverse roles ranging from carbon fixation to enteric pathogenesis. Current models for …