[HTML][HTML] The metabolic potential of plastics as biotechnological carbon sources–review and targets for the future

T Tiso, B Winter, R Wei, J Hee, J de Witt, N Wierckx… - Metabolic …, 2022 - Elsevier
The plastic crisis requires drastic measures, especially for the plastics' end-of-life. Mixed
plastic fractions are currently difficult to recycle, but microbial metabolism might open new …

Functions, Compositions, and Evolution of the Two Types of Carboxysomes: Polyhedral Microcompartments That Facilitate CO2 Fixation in Cyanobacteria and Some …

BD Rae, BM Long, MR Badger… - … and molecular biology …, 2013 - Am Soc Microbiol
Cyanobacteria are the globally dominant photoautotrophic lineage. Their success is
dependent on a set of adaptations collectively termed the CO2-concentrating mechanism …

Computational design of self-assembling protein nanomaterials with atomic level accuracy

NP King, W Sheffler, MR Sawaya, BS Vollmar… - Science, 2012 - science.org
We describe a general computational method for designing proteins that self-assemble to a
desired symmetric architecture. Protein building blocks are docked together symmetrically to …

A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia

SI Lee, S Celik, BA Logsdon, SM Lundberg… - Nature …, 2018 - nature.com
Cancers that appear pathologically similar often respond differently to the same drug
regimens. Methods to better match patients to drugs are in high demand. We demonstrate a …

A taxonomy of bacterial microcompartment loci constructed by a novel scoring method

SD Axen, O Erbilgin, CA Kerfeld - PLoS computational biology, 2014 - journals.plos.org
Bacterial microcompartments (BMCs) are proteinaceous organelles involved in both
autotrophic and heterotrophic metabolism. All BMCs share homologous shell proteins but …

Diverse bacterial microcompartment organelles

C Chowdhury, S Sinha, S Chun… - Microbiology and …, 2014 - Am Soc Microbiol
Bacterial microcompartments (MCPs) are sophisticated protein-based organelles used to
optimize metabolic pathways. They consist of metabolic enzymes encapsulated within a …

Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm

MJ Lee, J Mantell, L Hodgson, D Alibhai… - Nature chemical …, 2018 - nature.com
We have developed a system for producing a supramolecular scaffold that permeates the
entire Escherichia coli cytoplasm. This cytoscaffold is constructed from a three-component …

Solution structure of a bacterial microcompartment targeting peptide and its application in the construction of an ethanol bioreactor

AD Lawrence, S Frank, S Newnham, MJ Lee… - ACS synthetic …, 2014 - ACS Publications
Targeting of proteins to bacterial microcompartments (BMCs) is mediated by an 18-amino-
acid peptide sequence. Herein, we report the solution structure of the N-terminal targeting …

Bacterial microcompartments and the modular construction of microbial metabolism

CA Kerfeld, O Erbilgin - Trends in microbiology, 2015 - cell.com
Bacterial microcompartments (BMCs) are protein-bound organelles predicted to be present
across 23 bacterial phyla. BMCs facilitate carbon fixation as well as the aerobic and …

Selective molecular transport through the protein shell of a bacterial microcompartment organelle

C Chowdhury, S Chun, A Pang… - Proceedings of the …, 2015 - National Acad Sciences
Bacterial microcompartments are widespread prokaryotic organelles that have important
and diverse roles ranging from carbon fixation to enteric pathogenesis. Current models for …