Pyoderma gangrenosum

E Maverakis, AV Marzano, ST Le, JP Callen… - Nature Reviews …, 2020 - nature.com
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that presents with rapidly
developing, painful skin ulcers hallmarked by undermined borders and peripheral erythema …

Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment

A Alavi, LE French, MD Davis, A Brassard… - American journal of …, 2017 - Springer
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic disorder with prototypical
clinical presentations. Its pathophysiology is complex and not fully explained. Recent …

Diagnostic criteria of ulcerative pyoderma gangrenosum: a Delphi consensus of international experts

E Maverakis, C Ma, K Shinkai, D Fiorentino… - JAMA …, 2018 - jamanetwork.com
Importance Pyoderma gangrenosum is a rare inflammatory skin condition that is difficult to
diagnose. Currently, it is a “diagnosis of exclusion,” a definition not compatible with clinical …

Pathophysiology of pyoderma gangrenosum (PG): an updated review

SF Braswell, TC Kostopoulos… - Journal of the American …, 2015 - Elsevier
Pyoderma gangrenosum is a challenging skin condition to identify and treat because of its
multifactorial pathogenesis. It is a rare cutaneous manifestation diagnosed clinically by …

Neutrophilic dermatoses: pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease

CA Nelson, S Stephen, HJ Ashchyan… - Journal of the American …, 2018 - Elsevier
Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders that
present with unique clinical features but are unified by the presence of a sterile …

A comprehensive review of neutrophilic diseases

AV Marzano, A Borghi, D Wallach, M Cugno - Clinical reviews in allergy & …, 2018 - Springer
Neutrophilic dermatoses are a group of conditions characterized by the accumulation of
neutrophils in the skin and clinically presenting with polymorphic cutaneous lesions …

[HTML][HTML] Hidradenitis suppurativa is characterized by dysregulation of the Th17: Treg cell axis, which is corrected by anti-TNF therapy

B Moran, CM Sweeney, R Hughes, A Malara… - Journal of Investigative …, 2017 - Elsevier
Hidradenitis suppurativa (HS) is a chronic, inflammatory, and debilitating disease of hair
follicles with 1–4% prevalence and high morbidity. There is a dearth of information on the …

Autoinflammation in pyoderma gangrenosum and its syndromic form (pyoderma gangrenosum, acne and suppurative hidradenitis)

AV Marzano, G Damiani, I Ceccherini… - British Journal of …, 2017 - academic.oup.com
Background Pyoderma gangrenosum (PG) is a rare skin disease characterized clinically by
ulcers with undermined borders, and histologically by neutrophil‐rich infiltrates. PG may …

Pyoderma gangrenosum: a review of pathogenesis and treatment

C Ahn, D Negus, W Huang - Expert review of clinical immunology, 2018 - Taylor & Francis
Introduction: Pyoderma gangrenosum (PG) is a complex neutrophilic dermatosis that can
occur as an idiopathic disease, in association with systemic conditions such as inflammatory …

Insights into the pathogenesis of Sweet's syndrome

MS Heath, AG Ortega-Loayza - Frontiers in immunology, 2019 - frontiersin.org
Sweet's syndrome, also known as Acute Febrile Neutrophilic Dermatosis, is a rare
inflammatory condition. It is considered to be the prototype disease of neutrophilic …