Laboratory investigations provide physicians with objective data to aid in disease diagnosis,
clinical decision making, and patient follow up. Clinical interpretation of laboratory test …

The history of the theory of reference values can be written as an unfinished symphony. The
first movement, allegro con fuoco, played from 1960 to 1980: a mix of themes devoted to the …

Reference intervals are crucial decision-making tools aiding clinicians in differentiating
between healthy and diseased populations. However, for children such values often are …

Paediatric reference intervals based on samples from healthy children are difficult to
establish and consequently data are often from hospitalized children. Furthermore, biases …

Background The development and growth of children influence values of liver function tests.
This study aims to establish age-and gender-specific pediatric reference intervals of liver …

OBJECTIVES: Pediatric serum samples collected from healthy children in the CALIPER
(Canadian Laboratory Initiative in Pediatric Reference Interval) project are stored at− 80° C …

Background Vitamin D regulates bone mineral metabolism and skeletal development. Some
observational studies have suggested that prenatal vitamin D deficiency increases the risk of …

The clinical laboratory plays a critical role in healthcare delivery by providing objective data
on specific biomarkers that directly aid in the diagnosis and monitoring of a wide range of …

Age-specific paediatric reference intervals are used in interpretation of laboratory results.
However, interpretation may be problematic when a child just crosses an age bracket and …

OBJECTIVES: There are no direct comparisons of blood glucose values in samples
collected with barrier serum tubes (SST™) and NaF/potassium oxalate (NaF/KOx) plasma …