Extracellular vesicles (EVs) have emerged as an attractive liquid biopsy approach in the
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …

Opioids are substances derived from opium (natural opioids). In its raw state, opium is a
gummy latex extracted from Papaver somniferum. The use of opioids and their negative …

Abstract Background The United States is currently facing an opioid crisis. Novel tools to
better comprehend dynamic molecular changes in the brain associated with the opioid …

Extracellular vesicles (EVs), which express a repertoire of cargo molecules (cf. proteins,
microRNA, lipids, etc.), have been garnering a prominent role in the modulation of several …

Addiction is a chronic and relapsing brain disorder characterized by compulsive seeking
despite adverse consequences. There are both heritable and epigenetic mechanisms …

Hepatocellular carcinoma (HCC) is one of the most malignant cancers around the world.
However, the early biomarkers for its detection and treatment are limited currently …

Methamphetamine (MA) is the largest drug threat across the globe, with health effects
including neurotoxicity and cardiovascular disease. Recent studies have begun to link …

Stem cells drive embryonic and fetal development. In several adult tissues, they retain the
ability to self-renew and differentiate into a variety of specialized cells, thus contributing to …

Hepatocellular carcinoma (HCC) is a prevalent malignant tumor worldwide, with an
unsatisfactory prognosis, although treatments are improving. One of the main challenges for …

Objectives Drug abuse is one of the most severe global social and public health problems,
especially in China. However, objective blood biomarkers that are easy to detect are still in …