Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can
subsequently culminate in right heart failure and premature death. Emerging evidence …

Obstructive sleep apnea (OSA) is a prevalent, underdiagnosed disease that imposes a
significant impact on the health and wellbeing of patients and a financial burden on …

Background: Hemorrhagic shock (HS) is the major cause of death from trauma. Hemorrhagic
shock may lead to cellular hypoxia and organ damage. Our previous findings showed that …

Objective: High altitude and hypoxic preconditioning have cardioprotective effects by
increasing coronary vascularity, reducing post-ischemic injury, and improving cardiac …

Background Long-term exposure to a high-altitude environment with low pressure and low
oxygen can cause abnormalities in the structure and function of the heart, in particular the …

Published articles regarding the blood levels of vascular endothelial growth factor (VEGF) in
obstructive sleep apnea (OSA) patients are contradictory. The objective of this study was to …

Right ventricular (RV) function and eventually failure determine outcome in patients with
pulmonary arterial hypertension (PAH). Initially, RV responds to an increased load caused …

Atherosclerosis is a common pathologic condition that is affecting millions of people in their
large and small arteries, including the aorta, coronary, and cerebral arteries. Atherosclerotic …

Objective: To investigate the potential beneficial effect of bosentan in ameliorating fibrotic
agents in diabetic mice. Methods: Male 6-week old C57BL/6 mice were divided into 3 …

Exhaustive exercise can cause subclinical inflammation to the heart, as it is an oxidative
tissue that works continuously. The effect of exhaustive exercise on left and right ventricles …