Diverticular disease is a common clinical problem, particularly in industrialized countries. In
most cases, colonic diverticula remain asymptomatic throughout life and sometimes are …

This article reviews epidemiological evidence of heritability and putative mechanisms in
diverticular disease, with greatest attention to 3 recent studies of genetic associations with …

Menthol is the major constituent of peppermint oil, an herbal preparation commonly used to
treat nausea, spasms during colonoscopy and irritable bowel disease. The mechanism …

Colonic diverticular disease is a common health care issue which has historically been
attributed to western countries and older age population. Recent studies have shown a rise …

Diverticula of the colon are pseudodiverticula defined by multiple outpouchings of the
mucosal and submucosal layers penetrating through weak spots of the muscle coat along …

Aim The real prevalence of symptomatic uncomplicated diverticular disease (SUDD) is still
unknown. The aim of this study was to assess the prevalence of SUDD, post-diverticulitis …

Background Neuro‐transmission impairment could be associated to motility changes
observed in patients with diverticular disease. Therefore, the objective was to characterize …

Background Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor
known to promote the survival and maintenance of neurons not only in the developing but …

Methods MS or SMCs were isolated from specimens of human distal colon of 18 patients
undergoing surgery for non-obstructive colonic cancer, among them 9 with SUDD …

Background: Diverticular disease (DD) is a common gastrointestinal inflammatory disorder
associated with an enteric neuropathy. Although enteric glial cells (EGCs) are essential …