Pathophysiology, diagnosis, and management of endometriosis

AW Horne, SA Missmer - bmj, 2022 - bmj.com
Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment

G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

Health-related toxicity of emerging per-and polyfluoroalkyl substances: Comparison to legacy PFOS and PFOA

LJL Espartero, M Yamada, J Ford, G Owens… - Environmental …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are highly persistent, manufactured chemicals
used in various manufacturing processes and found in numerous commercial products. With …

The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain

ME Salliss, LV Farland, ND Mahnert… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?

RM Marquardt, TH Kim, JH Shin, JW Jeong - International journal of …, 2019 - mdpi.com
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …

Risk factors for atonic postpartum hemorrhage: a systematic review and meta-analysis

HB Ende, MJ Lozada, DH Chestnut… - Obstetrics & …, 2021 - journals.lww.com
OBJECTIVE: To identify and quantify risk factors for atonic postpartum hemorrhage. DATA
SOURCES: PubMed, CINAHL, EMBASE, Web of Science, and and ClinicalTrials. gov …

Assessing research gaps and unmet needs in endometriosis

S As-Sanie, R Black, LC Giudice, TG Valbrun… - American journal of …, 2019 - Elsevier
Endometriosis, a systemic disease that is often painful and chronic, affects∼ 10% of
reproductive-age women. The disease can have a negative impact on a patient's physical …

Physiologic events of embryo implantation and decidualization in human and non-human primates

MA Ochoa-Bernal, AT Fazleabas - International journal of molecular …, 2020 - mdpi.com
Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility

G Fiorentino, D Cimadomo, F Innocenti… - Human …, 2023 - academic.oup.com
BACKGROUND Folliculogenesis occurs in the highly dynamic environment of the ovary.
Follicle cyclic recruitment, neo-angiogenesis, spatial displacement, follicle atresia and …