New insights into lipid metabolism and prostate cancer

Z Zhang, W Wang, P Kong, K Feng… - International …, 2023 - spandidos-publications.com
Prostate cancer (PCa) is the most common malignant tumor of the male urological system
and poses a severe threat to the survival of middle‑aged and elderly males worldwide. The …

A Novel HOXA10-Associated 5-Gene–Based Prognostic Signature for Stratification of Short-term Survivors of Pancreatic Ductal Adenocarcinoma

SG Kisling, P Atri, A Shah, JL Cox, S Sharma… - Clinical Cancer …, 2023 - AACR
Purpose: Despite the significant association of molecular subtypes with poor prognosis in
patients with pancreatic ductal adenocarcinoma (PDAC), few efforts have been made to …

A review of prostate organogenesis and a role for iPSC-derived prostate organoids to study prostate development and disease

A Buskin, P Singh, O Lorenz, C Robson… - International journal of …, 2021 - mdpi.com
The prostate is vulnerable to two major age-associated diseases, cancer and benign
enlargement, which account for significant morbidity and mortality for men across the globe …

Characterization of a prostate-and prostate cancer-specific circular RNA encoded by the androgen receptor gene

J Luo, Y Li, W Zheng, N Xie, Y Shi, Z Long, L Xie… - … Therapy-Nucleic Acids, 2019 - cell.com
The linear mRNAs transcribed under alternative RNA splicing and overexpression/
amplification of the androgen receptor (AR) gene are poor prognostic biomarkers of castrate …

HOXA10 promote pancreatic cancer progression via directly activating canonical NF-κB signaling pathway

J Li, J Chang, J Wang, D Xu, M Yang, Y Jiang… - …, 2022 - academic.oup.com
Background Although transcription factor homeobox A10 (HOXA10) plays an important role
in regulating the development of the pancreas, a pathway of HOXA10 participates in …

Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer

Z Long, L Deng, C Li, Q He, Y He, X Hu, Y Cai… - Cell Death & …, 2021 - nature.com
The rising of a highly aggressive subtype of castration-resistant prostate cancer (CRPC)
named treatment-induced neuroendocrine prostate cancer (t-NEPC) after androgen …

Characterization of HMGB1/2 interactome in prostate cancer by yeast two hybrid approach: potential pathobiological implications

A Barreiro-Alonso, M Cámara-Quílez… - Cancers, 2019 - mdpi.com
High mobility group box B (HMGB) proteins are pivotal in the development of cancer.
Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement …

Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma

D Gong, H Zhu, L Zeng, R Hu, J Hu… - … Biology and Medicine, 2021 - journals.sagepub.com
Deregulation of HOX transcription factor family has frequently been observed in multiple
human cancers; however, their role in nasopharyngeal carcinoma remains largely unclear …

LncRNA HOXA10-AS promotes the progression of esophageal carcinoma by regulating the expression of HOXA10

J Kuai, K Wu, T Han, W Zhai, R Sun - Cell Cycle, 2023 - Taylor & Francis
Esophageal cancer (EC) remains a primary cause of cancer-associated fatality worldwide
and is characterized by poor prognosis. HOXA10-AS is reported to be relevant with the …

[PDF][PDF] HOXA10 promotes the development of bladder cancer through regulating FOSL1.

YP Cui, M Xie, WX Pan, ZY Zhang… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: This study was aimed to investigate the expression characteristics of HOXA10
in bladder cancer (BCa), and to further study whether it can promote the development of …